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Accelerated Hypofractionated Whole Breast Irradiation Plus Sequential Boost Versus Concomitant Boost Following BCS

Radiotherapy Side Effect Clinical Trial

Official title:
Randomized Prospective Study of Accelerated Hypofractionated Whole Breast Irradiation Plus Sequential Boost Versus Concomitant Boost Following Breast Conservative Surgery

Clinical Trial Summary

A prospective study comparing sequential versus concomitant radiotherapy boost in breast conservative therapy.

Clinical Trial Description

This study is a prospective randomized non-inferiority trial of accelerated hypofractionated whole breast irradiation plus sequential boost versus concomitant boost after breast conservative surgery. It will be conducted on 124 patients who will be randomized using permuted blocks. The primary outcome measured is the cosmetic outcome, while secondary outcomes are patient satisfaction (using breast questionnaire), acute toxicity (using RTOG acute toxicity scoring criteria), and late toxicity (using RTOG late toxicity scoring criteria). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03710733
Study type Interventional
Source National Cancer Institute, Egypt
Contact
Status Active, not recruiting
Phase N/A
Start date June 1, 2018
Completion date June 30, 2021
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