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Radiculopathy clinical trials

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NCT ID: NCT06041347 Not yet recruiting - Endometriosis Clinical Trials

Learning Curve for the Visualization of Sacral Plexus on TVS

PlexUS
Start date: October 1, 2023
Phase:
Study type: Observational

The purpose of this prospective study was to evaluate the learning curve of TVUS (transvaginal ultrasound) for the visualization of sacral nerve roots and sacral plexus on gynecological transvaginal ultrasound. The investigators aim to evaluate to evaluate the number needed to gain competence or to review the level of competence.

NCT ID: NCT05971329 Not yet recruiting - Disc Degeneration Clinical Trials

Pilot Study of ZetaFuseā„¢ Bone Graft for the Treatment of Cervical Degenerative Disc Disease

Start date: September 2024
Phase: Early Phase 1
Study type: Interventional

The goal of this pilot clinical trial is to test the safety and preliminary performance of the ZetaFuse Bone Graft in patient requiring fusion of the C3-C7 vertebral bones due to pain or loss of neurological function. Participants will be treated with ZetaFuse during surgical intervention to reduce pain and the loss of neurological function.

NCT ID: NCT05960487 Not yet recruiting - Clinical trials for Cervical Radiculopathy

Effect of Cervical Multifidus Muscle Area on Interlaminar Epidural Steroid Injection Outcomes

Start date: July 20, 2023
Phase:
Study type: Observational

Cervical radiculopathy is one of the most important causes of chronic neck pain. Cervical epidural steroid injections including interlaminar approach are frequently used for treatment option in patients that more conservative modalities are ineffective. Paraspinal muscles have an important role in supporting neck movements and providing stability of the cervical spine. The multifidus muscle, located in the deepest part of the neck extensor muscle group, has become the muscle that is frequently emphasized in spinal pain in recent years. In the literature, it has been shown that the multifidus muscle on the affected side is atrophied in patients with cervical radiculopathy. Although many factors are known to be effective on the outcomes of cervical interlaminar epidural injection, there are limited data on the effect of the multifidus muscle area. In this retrospective study, it was planned to investigate the effect of the multifidus muscle area on the results of cervical interlaminar epidural steroid injection.

NCT ID: NCT05793528 Not yet recruiting - Clinical trials for Lumbar Disc Herniation

The Effect of Ultrasound Guidance on Radiation Dose and Procedure Time in Lumbar Transforaminal Epidural Injection

Start date: May 1, 2023
Phase:
Study type: Observational

Low back pain is one of the leading causes of disability, and its social burden and economic cost are quite high. Although there are many causes that can lead to low back pain, radicular pain, which develops mostly secondary to lumbar disc hernias, is one of the most common pathologies. Epidural corticosteroid and local anesthetic injections are an important treatment option in the treatment of lumbar radicular pain that does not respond to conservative methods. For fluoroscopy-guided epidural injections; transforaminal, interlaminar and caudal approaches may be preferred. It is accepted as the superiority of the transforaminal approach that it allows access to the area of pathology, thus to the anterior epidural area where inflammatory mediators are more concentrated, and that it can spread to the target specifically around the inflamed nerve roots. In transforaminal epidural injections, the use of ultrasound as the sole imaging tool throughout the entire procedure is still not appropriate, as subbony structures cannot be visualized. However, ultrasound can be integrated at any stage of the process. Thus, the relatively inexpensive cost, portability, and ability to show non-osseous tissues of ultrasonography are utilized, particularly in terms of reducing radiation exposure. Gofeld et al. claimed that ultrasound-guided transforaminal epidural injection could be performed by targeting the posterior part of the vertebral body. However, in cases where the lamina is wide and covers the posterior of the vertebral body, it may not be possible to sonographically view the vertebral body. In addition, although the intervertebral disc is differentiated from the corpus, loss of fluid content in the elderly can cause acoustic shadowing in the disc. This may result in accidental intra-disc injections. Finally, even if the target point is reached, it is not possible to show intravascular spread at this level ultrasonographically. Therefore, in our opinion, this method is unreliable for transforaminal epidural injections. Another study used ultrasound and fluoroscopy together for transforaminal epidural injections. After imaging the lamina of the relevant vertebral level sonographically, the needle is directed to the lateral edge of the lamina, then fluoroscopic imaging is performed after it passes under the lamina with the loss of resistance technique. However, it should be known that the loss of resistance technique is not a suitable and reliable method in transforaminal injections. In addition, since it is not known how far the lamina has progressed after it has passed under the bone, in other words, imaging guidance is disabled in this part of the process. In our clinic, we use ultrasonography and fluoroscopy methods in an integrated way (hybrid method) for transforaminal epidural injections. For this purpose, we proceed to fluoroscopic imaging immediately after the spinal needle is advanced to the lateral edge of the lamina at the vertebral level where there is pathology with ultrasound. We think that with this method, we continue to stay in the safe window and reduce the radiation dose and procedure time. Based on this, we determined the aim of this study as the effect of including ultrasonography guidance in transforaminal epidural injections on radiation dose and procedure time.

NCT ID: NCT05749185 Not yet recruiting - Clinical trials for Chronic Cervical Radiculopathy

High Versus Standard Voltage Pulsed Radiofrequency for Cervical Nerve Roots Injection in Refractory Chronic Unilateral Cervical Radicular Pain

Start date: February 22, 2023
Phase: N/A
Study type: Interventional

Patients with refractory cervical radiculopathy can get benefit from radiofrequency ablation using specific voltage current to obtund chronic brachialgia. We will compare standard versus supra-voltage current in the efficacy of ablation using numeric rating scale as a primary outcome.

NCT ID: NCT05729022 Not yet recruiting - Clinical trials for Radiculopathy Lumbar

Ultrasound-Guided Microendoscopic Versus Fluoroscopic-Guided Lumbar Transforaminal Epidural Steroid Injections

Start date: December 1, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the Microendoscopic combined with ultrasound technique to the standard routinely used X-ray guided transforaminal steroid injection technique.

NCT ID: NCT05610553 Not yet recruiting - Low Back Pain Clinical Trials

Application of 3D Printing Guide Plate in Percutaneous Disc Decompression

Start date: December 10, 2022
Phase: N/A
Study type: Interventional

Application of 3D printing guide plate in percutaneous disc decompression

NCT ID: NCT05487690 Not yet recruiting - Low Back Pain Clinical Trials

Application of 3D Printing Guide Plate in Spinal Minimally Invasive and Interventional Surgeries

Start date: October 20, 2022
Phase: N/A
Study type: Interventional

Application of 3D printing guide plate in spinal minimally invasive and interventional surgeries

NCT ID: NCT05392933 Not yet recruiting - Clinical trials for Lumbar Radiculopathy

Investigation of the Presence of Piriformis Syndrome Accompanying Lumbar Radiculopathy

Start date: January 15, 2023
Phase: N/A
Study type: Interventional

Piriformis syndrome is a neuromuscular disorder that is characterized by piriformis muscle tenderness, hip, and leg pain, and may be accompanied by compression or irritation of the sciatic nerve under the piriformis muscle. There are many studies in the literature to establish diagnostic criteria for piriformis syndrome, and there is still no clear consensus on these criteria. However, cases with lumbar radiculopathy were accepted as exclusion criteria in all these studies. The aim of our study is to investigate whether lumbar radiculopathy and piriformis syndrome can coexist. For this reason, a diagnostic piriformis muscle injection under ultrasonography guidance is planned for patients with lumbar radiculopathy who also have a prediagnosis of piriformis syndrome clinically.

NCT ID: NCT05314049 Not yet recruiting - Low Back Pain Clinical Trials

Effects of Sustained Natural Apophyseal Glides in Combination With McKenzie Extension Protocol in the Management of Discogenic Low Back Pain

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

Lumbar degenerative disc disease and discogenic low back pain is comparatively common and disabling musculoskeletal condition. McKenzie's extension protocol is considered to be the gold standard physical therapy treatment for persons with acute discogenic low back pain, however the evidence is deficient in terms of additive benefits of sustained natural apophyseal glides in the management of discogenic low back pain. Thus, the current study will not only look into the positive effects of McKenzie's extension protocol in the management discogenic low back pain, but will also look into the additive benefits of sustained natural apophyseal glides in combination with McKenzie's extension protocol in the management of discogenic low back pain.