Urinary Incontinence Clinical Trial
Official title:
Mechanical Nerve Stimulation in the Treatment of Post Prostatectomy Incontinence
During transcutaneous mechanical nerve stimulation in spinal cord injured men an increase in
pressure was observed in the external urethral sphincter along with an increase in bladder
capacity. In a subsequent study it was demonstrated that Transcutaneous Mechanical Nerve
Stimulation (TMNS) in women could induce pressure increment of the external urethral
sphincter. A pilot study have since shown that after 6 weeks of stimulation 24 out of 33
women suffering from urinary stress incontinence were able to contract their pelvic floor
muscles and had become free of symptoms. Another pilot study has shown promising effect on
the overactive bladder syndrome. Furthermore pilot studies in men who are incontinent after
a radical prostatectomy have shown promising results. A randomized investigation of TMNS
applied in the immediate period after a radical prostatectomy to investigate effects on both
continence and erectile function is on going.
The present study aims to treat urinary incontinence in men who are still incontinent more
than 1 year after a radical prostatectomy. A medical vibrator is used daily for a period of
6 weeks and the results of the treatment is then evaluated. The participants will be
randomized to 2 groups. Group 1 starts vibration treatment at base line and group 2 starts
after 6 weeks when group 1 is done. The groups are compared at baseline, at 6 weeks and at
12 weeks.
The stimulation will be performed at the frenulum of the glans penis every day for 6 weeks
with an amplitude of 2 mm and a frequency of 100 Hz. Results will be evaluated on the basis
of questionnaires, micturition diaries and diaper tests.
If the investigators are able to demonstrate a significant reduction in the incontinence
symptoms in the subjects the investigators asses that vibration can be a way of
reestablishing normal continence in men after a radical prostatectomy.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Treatment
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