Temporal Pattern of Circulating DNA for Patients Receiving Irradiation

Radiation Clinical Trial

Official title:

Temporal Pattern of Circulating DNA for Patients Receiving Total Body Irradiation

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT01099020
• Other study ID #: ULAB10008
• Status: Terminated
• Phase: N/A
• First received: April 2, 2010
• Last updated: May 29, 2015
• Start date: April 2010
• Est. completion date: December 2011

Study information

• Verified date: May 2015
• Source: University of Rochester
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

The purpose of the research study is to test a measurement tool that will determine the radiation dose people receive when they have been accidentally exposed to radiation. This test will be done using a small amount of blood and known dose of radiation.

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 13
• Est. completion date: December 2011
• Est. primary completion date: December 2011
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patient must be scheduled to undergo Total Body Irradiation (TBI) as part of a conditioning regime for a Bone Marrow Transplant. OR, Be scheduled to undergo Radiation Therapy treatment for a malignancy or other disease and have a radiation treatment field that contains at least 2 liters of tissue receiving at least 2 Gy radiation dose over the first 5 days of treatment.

• Patient must be willing to have blood draws as defined below.

• Patient must provide study-specific informed consent prior to study entry.

• Hemoglobin=8.

• Age = 18, but not older than age 60.

Exclusion Criteria:

• Patients not meeting the above inclusion criteria.

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

• Radiation

Locations

Country	Name	City	State
United States	University of Rochester	Rochester	New York

Sponsors (1)

Lead Sponsor	Collaborator
University of Rochester

Country where clinical trial is conducted

United States,