Effects of Subcutaneously Infiltrated Nicardipine on the Success Rate of Radial Artety Cannulation

Radial Artery Cannulation Clinical Trial

Official title:

Effects of Subcutaneously Infiltrated Nicardipine on the Success Rate of Radial Artety Cannulation

Clinical Trial Details — Status: Enrolling by invitation

Administrative data

• NCT number: NCT05920538
• Other study ID #: 764/2565(IRB3)
• Status: Enrolling by invitation
• Phase: N/A
• Start date: March 13, 2023
• Est. completion date: January 2024

Study information

• Verified date: June 2023
• Source: Mahidol University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The goal of this study is to compare the success rate of subcutaneously infiltrated nicardipine to normal saline in radial artery cannulation

Recruitment information / eligibility

• Status: Enrolling by invitation
• Enrollment: 190
• Est. completion date: January 2024
• Est. primary completion date: December 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 75 Years

Eligibility

Inclusion Criteria:

• age 18-75 years

• the patient who need to arterial line

Exclusion Criteria:

• allergy to nicardipine

• history of peripheral artery disease

• BMI > 40 kg/m2

• unwilling to participate or denial of informed consent

Related Conditions & MeSH terms

• Radial Artery Cannulation

Intervention

Drug:
• Nicardipine
Subcutaneous infiltrate drug at puncture site by ultrasound-guided

Other:
• Normal saline
Subcutaneous infiltrate NSS at puncture site by ultrasound-guided

Locations

Country	Name	City	State
Thailand	Anesthesiology Department	Bangkok

Sponsors (1)

Lead Sponsor	Collaborator
Mahidol University

Country where clinical trial is conducted

Thailand, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Success rate of radial artery cannulation since first skin puncture	Success rate of radial artery cannulation since first skin puncture	10 minute from puncture at skin
Secondary	radial artery diameter	Pre-induction radial artery diameter, post-induction radial artery diameter, radial artery diameter after subcutaneous infiltration at 0,1,2 and 3 minute	Pre-induction to 3 minute after subcutaneous infiltration
Secondary	Time from first skin puncture to success cannulation	Time from first skin puncture to present of arterial wave form, assessed less than 10 minutes	10 minutes