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Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT05089994
Other study ID # 01060264751
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date October 6, 2021
Est. completion date June 25, 2024

Study information

Verified date June 2024
Source Assiut University
Contact Hassan Mostafa abdelbaky ahmed, Master
Phone 01060264751
Email hassan.mostafa9444@gmail.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

To compare the postoperative analgesic effect of two ultrasound guided approaches of quadratus lumborum block (QLB) (anterior and intramuscular) for radical cystectomy.


Description:

The quadratus lumborum block (QLB) is one of the abdominal wall block techniques used to anesthetize thoracolumbar nerves . The QLB technique was described initially by Blanco et al. in 2007 (not published), then reported initially by Kadam in 2013. Since then, QLB has evolved with the development of the ultrasound-guided nerve block. To date, several randomized controlled trials have reported effective postoperative analgesia, with non-intramuscular QLB for cesarean sections, laparoscopic gynecologic surgery and hip hemiarthroplasty . The intramuscular QLB (QLBi) technique was first reported by. This approach is different from others in tubouchi for QLB; although the injection target sites of the other approaches are planes around the quadratus lumborum muscle, the intramuscular approach penetrates the fascia of the quadratus lumborum muscle, where local anesthetics are injected. Therefore, QLBi is relatively easier to perform compared with other QLB approaches. The incidence of urinary bladder cancer in the Middle East and Africa is greater in areas with high rather than low SH prevalence.


Recruitment information / eligibility

Status Recruiting
Enrollment 60
Est. completion date June 25, 2024
Est. primary completion date June 4, 2024
Accepts healthy volunteers No
Gender All
Age group 40 Years to 70 Years
Eligibility Inclusion Criteria: - Age: 40-70years. - BMI: 20-30 kg.m2 - Sex: both males and females. - American Society of Anesthesiologists (ASA )physical status: I-III. - Operation: radical cystectomy Exclusion Criteria: - • Patient's refusal to participate in the study. - known allergy to local anesthesia (LA), - coagulopathy or thrombocytopenia, - body mass index (BMI) above 30 kg .m 2, and infection at site of injection. - Chronic pain syndromes, - Prolonged opioid medication, - Patients on regular use of analgesic or who received analgesic 24 h before surgery

Study Design


Related Conditions & MeSH terms


Intervention

Procedure:
US guided injection
using 2.5mg/kg of 0.25% bupivacaine diluted in a 20 mL syringe of normal saline , received ultrasound-guided quadratus lumborum.

Locations

Country Name City State
Egypt Assuit university urology hospital Assiut

Sponsors (1)

Lead Sponsor Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

Outcome

Type Measure Description Time frame Safety issue
Primary Evaluate the first call for rescue analgesia The time of the first call of analgesia is recorded 24hours after recovery From anesthesia
Secondary Total doses of morphine required Doses of morphine required postoperative 24hours after recovery from anesthesia
See also
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Recruiting NCT04402411 - Quadratus Lumborum Block vs Transversus Abdominis Plane Block in Bladder Cancer Surgeries N/A
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Completed NCT05713643 - ESPB vs PVB vs QLB After Pelvi-ureteric Surgeries N/A
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Completed NCT03437187 - The Beneficial Effect of Quadratus Lumborum Block After Laparoscopic Cholecystectomy N/A
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Recruiting NCT06451354 - Postoperative Analgesia After Cesarean Section; Comparison Among Ultrasound Guided Erector Spinae, Quadratus Lumborum or Transversus Abdominis Plane Blocks N/A