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Purpura clinical trials

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NCT ID: NCT00168038 Completed - Clinical trials for Immune Thrombocytopenic Purpura

Treatment of Chronic Immune Thrombocytopenic Purpura (ITP) With Intravenous Immunoglobulin IgPro10

Start date: December 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy, tolerability and safety of IgPro10 in the treatment of patients with chronic immune thrombocytopenic purpura (ITP). The main efficacy parameter is the proportion of patients responding to treatment by an increase of platelet count to ≥ 50 x 10^9/L.

NCT ID: NCT00162006 Completed - Clinical trials for Immune Thrombocytopenic Purpura (ITP)

Efficacy and Safety Study of a 10% Triple Virally Reduced Intravenous Immune Globulin Solution in Adult Subjects With Chronic Idiopathic Thrombocytopenic Purpura

Start date: January 13, 2003
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate whether Immune Globulin Intravenous (Human), 10% TVR (Triple Virally Reduced) Solution is an effective and safe treatment in patients with chronic idiopathic thrombocytopenic purpura.

NCT ID: NCT00161564 Withdrawn - Clinical trials for Idiopathic Thrombocytopenic Purpura (ITP)

A Trial to Treat Patients With ITP Who Do Not Achieve a Durable Response to Rituxan Alone

Start date: February 2004
Phase: Phase 2
Study type: Interventional

The purpose of this research study is to compare the efficacy and safety of higher doses of rituximab to a combination of standard doses of Rituxan + CVP (Cyclophosphamide, Vincristine, and Prednisone) in patients with chronic Idiopathic Thrombocytopenic Purpura (ITP who did not respond to or relapsed after standard doses of rituximab.

NCT ID: NCT00157079 Completed - Clinical trials for Primary Immunodeficiency Diseases (PID)

Safety and Efficacy Study of a 10% Intravenous Immune Globulin Solution in Subjects With Primary Immunodeficiency Disorders

Start date: June 25, 2002
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the safety and efficacy of Immune Globulin Intravenous (Human), 10% (IGIV 10%) in subjects with primary immunodeficiency disorders.

NCT ID: NCT00151840 Completed - Clinical trials for Purpura, Thrombocytopenic, Idiopathic

Efficacy and Safety of IVIG-L in ITP Patients

Start date: October 2001
Phase: Phase 3
Study type: Interventional

The efficacy and safety of a liquid intravenous immunoglobulin product, IVIG-L, in patients with ITP will be assessed and compared with data obtained from literature.

NCT ID: NCT00128882 Completed - Clinical trials for Idiopathic Thrombocytopenic Purpura

Treatment of Idiopathic Thrombocytopenic Purpura (ITP) With Subcutaneously Administered Anti-D

Start date: November 2004
Phase: Phase 2
Study type: Interventional

The purpose of this study is to describe the effect of anti-D on symptoms and platelet count in children suffering from unexplainable low platelet counts, when anti-D is administered as an injection under the skin. The hypothesis is that the injection with anti-D under the skin is as effective as anti-D given in a vein.

NCT ID: NCT00117143 Completed - Clinical trials for Thrombocytopenic Purpura

Amgen Megakaryopoiesis Protein 2 (AMG 531) in Thrombocytopenic Subjects With Immune Thrombocytopenic Purpura (ITP)

Start date: December 2, 2002
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to assess the safety and tolerability of AMG 531 (romiplostim), a novel thrombopoiesis-stimulating peptibody, and its effect on platelet counts in adults with immune thrombocytopenic purpura.

NCT ID: NCT00116688 Completed - Thrombocytopenia Clinical Trials

Open Label Extension Study of Romiplostim (AMG 531) in Thrombocytopenic Patients With Immune (Idiopathic) Thrombocytopenic Purpura (ITP)

Start date: August 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the safety of romiplostim as a long-term treatment in thrombocytopenic subjects with ITP, to evaluate the long-term platelet response to romiplostim, and to evaluate changes in patient reported outcomes due to the use of romiplostim. Participants must have previously completed a romiplostim ITP study.

NCT ID: NCT00111475 Completed - Clinical trials for Idiopathic Thrombocytopenic Purpura

Evaluating the Safety and Efficacy of Romiplostim (AMG 531) in Thrombocytopenic Subjects With Immune Thrombocytopenic Purpura (ITP)

Start date: July 1, 2002
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to evaluate the safety and tolerability of romiplostim in thrombocytopenic patients with ITP.

NCT ID: NCT00107913 Recruiting - Clinical trials for Autoimmune Thrombocytopenic Purpura

Study of Doxil in the Treatment of Patients With Refractory Idiopathic Thrombocytopenic Purpura

Start date: September 2001
Phase: Phase 2
Study type: Interventional

This study is designed to evaluate the efficacy and safety of single agent Doxil in the treatment of patients with refractory ITP (Idiopathic Thrombocytopenic Purpura).