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Purging (Eating Disorders) clinical trials

View clinical trials related to Purging (Eating Disorders).

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NCT ID: NCT06198023 Recruiting - Anorexia Nervosa Clinical Trials

Targeting Social Function to Improve Outcomes in Eating Disorders

SF-ED
Start date: February 28, 2024
Phase: N/A
Study type: Interventional

Social processing and cognition are often altered in patients with eating disorders. The goal of this clinical trial is to assess two different social therapeutic interventions -- one educational, one interactive -- for their effectiveness in improving clinical outcomes in patients with eating disorders. Patients in both interventions will receive education about social function in eating disorders, but those in the interactive treatment group will complete an additional collaborative art task. Participants will: - attend a baseline study visit to complete clinical interviews, cognitive testing, and behavioral tasks - complete a pre-intervention assessment with questionnaires - attend eight sessions of their assigned treatment group over the course of 12 weeks - complete three virtual follow-up assessments 4, 8, and 12 months from their baseline - attend a final study visit to repeat some clinical interviews, cognitive testing, and behavioral tasks Researchers will compare changes in eating disorder, mood, and anxiety symptoms as well as test results from baseline and final study visits for each group to see if - patients can be treated effectively with education alone or if an interactive group component produces additional benefits - cognitive and behavioral task performance are associated with recovery or illness state.

NCT ID: NCT05509257 Recruiting - Eating Disorders Clinical Trials

Naltrexone Neuroimaging in Teens With Eating Disorders

NN-RCT
Start date: September 17, 2022
Phase: Early Phase 1
Study type: Interventional

Using a randomized, placebo-controlled, crossover study, this study will evaluate functional magnetic resonance imaging (fMRI) as a pharmacodynamic biomarker of opioid antagonism in adolescents with eating disorders. The hypothesis is that fMRI will be able to detect acute reward pathway modulation by naltrexone (an opioid antagonist) in pre-defined regions of interest (anterior cingulate cortex, nucleus accumbens, dorsolateral prefrontal cortex).

NCT ID: NCT05073679 Terminated - Eating Disorders Clinical Trials

Oral Naltrexone In Pediatric Eating Disorders

ONPED
Start date: April 22, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

The objective of this study is to evaluate the effectiveness of oral naltrexone tablets in pediatric and adolescent eating disorders, in particular anorexia nervosa and bulimia nervosa, as compared to placebo. Study participants will be patients in a partial hospitalization program or intensive outpatient program for eating disorder.

NCT ID: NCT04935931 Completed - Eating Disorders Clinical Trials

Naltrexone Neuroimaging

EDIT-N2
Start date: July 16, 2021
Phase: Early Phase 1
Study type: Interventional

The purpose of this open-label, pilot study is to evaluate fMRI as a biomarker of opioid antagonism in adolescents with ED. Modulation of brain activation will be examined in regions of interest by fMRI using a food-specific and general reward task in adolescents with ED in a pre/post design.

NCT ID: NCT03429114 Completed - Binge Eating Clinical Trials

Emotion Regulation in Binge Eating and Purging Among Adolescents

Start date: October 15, 2017
Phase:
Study type: Observational

The study will examine the neural and behavioral correlates of emotion regulation in adolescents engaging in binge eating and/or purging and healthy adolescents. Furthermore, it will look at the influence of executive function on emotion regulation in this population. This study will allow us to gain further understanding of the neural basis of emotion regulation in this age group. Moreover, this study supports the need to develop new treatment approaches based on a better understanding of the brain processes associated with eating disorders.

NCT ID: NCT02716831 Recruiting - Bulimia Nervosa Clinical Trials

Improving Treatments for Bulimia Nervosa: Innovation in Psychological Interventions for Regulating Eating

INSPIRE
Start date: May 2015
Phase: N/A
Study type: Interventional

The purpose of the study is to test a novel, acceptance-based behavioral treatment for bulimia nervosa (BN) in adults. This treatment is a type of individual psychotherapy called Nutritional Counseling And Acceptance-Based Therapy (N-CAAT) that enhances existing cognitive behavioral therapy (CBT) for BN by incorporating acceptance-based behavioral strategies and nutritional counseling to help patients eliminate BN symptoms.