Clinical Trials Logo
  1. Home
  2. Pulmonary Nodules
  3. NCT05067023

Evaluation for Benign and Malignant Pulmonary Ground-glass Nodules Based on MRI Dynamic Contrast Enhanced Imaging

Pulmonary Nodules Clinical Trial

Official title:
Evaluation for Benign and Malignant Pulmonary Ground-glass Nodules Based on MRI Dynamic Contrast Enhanced Imaging

Clinical Trial Summary

Computed tomography (CT) is critical for the diagnosis of lung nodules as well as for therapeutic management. Repeated CT examinations will raise the issue of the cumulative radiation dose and subsequent risk of cancer, thus pushing the need for imaging techniques using low or no radiation dose. Magnetic Resonance Imagery (MRI) with ultrashort echo time (UTE) pulse sequences with high signal-to-noise and spatial resolution is a promising alternative for lung nodules imaging.The purpose of the study is to evaluate the value of dynamic contrast-enhanced MR imaging (DCE-MRI) to discriminate of malignant from benign lesions.

Clinical Trial Description

Computed tomography (CT) is critical for the diagnosis of lung nodules as well as for therapeutic management. Repeated CT examinations will raise the issue of the cumulative radiation dose and subsequent risk of cancer, thus pushing the need for imaging techniques using low or no radiation dose. Magnetic Resonance Imagery (MRI) with ultrashort echo time (UTE) pulse sequences with high signal-to-noise and spatial resolution is a promising alternative for lung nodules imaging.The purpose of the study is to evaluate the value of DCE-MRI to discriminate of malignant from benign lesions.In this study, the investigators are going to validate the efficacy of the DCE-MRI for diagnosing early lung cancer by comparing results of the pre-surgery MRI imaging with the post-surgery pathology. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05067023
Study type Interventional
Source Qianfoshan Hospital
Contact
Status Not yet recruiting
Phase N/A
Start date November 20, 2021
Completion date March 15, 2023
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT06056999 - New Method to Differentiate Benign and Malignant Pulmonary Nodules.
Recruiting NCT04182893 - Clinical Study of ctDNA and Exosome Combined Detection to Identify Benign and Malignant Pulmonary Nodules
Active, not recruiting NCT03651986 - Diagnostic and Monitoring Significance of ctDNA Methylation Analysis by NGS in Benign and Malignant Pulmonary Nodules
Completed NCT02146131 - Ultrathin Bronchoscope and Radial Endobronchial Ultrasound (R-EBUS) With Fluoroscopy Versus Standard Fiberoptic Bronchoscopy (FB) (P00029233 ) N/A
Recruiting NCT04462185 - A Prospective Cohort Study of Chinese Patients With Pulmonary Nodules: Prediction of Lung Cancer Using Noninvasive Biomarkers
Recruiting NCT04690790 - Pulmonary Nodule Localization Prospective Validation
Recruiting NCT05525260 - Limonene for Pulmonary Nodule Chemoprevention Phase 2
Completed NCT00629460 - A Pilot Study of PET-CT in the Assessment of Pulmonary Nodules in Children With Malignant Solid Tumors N/A
Completed NCT03420885 - Effects of Ba Duan Jin for Patients With Pulmonary Nodules N/A
Active, not recruiting NCT05091437 - DOuBLED - Doubling Outcomes by Lung Cancer Early Diagnosis