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Pulmonary Function clinical trials

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NCT ID: NCT03193892 Recruiting - Pulmonary Function Clinical Trials

A National Registry on Chinese Patients With Lymphangioleiomyomatosis

Start date: January 1, 2017
Phase:
Study type: Observational [Patient Registry]

Pulmonary lymphangioleiomyomatosis (LAM), a disease characterized by diffuse cystic changes in the lung, is a rare disorder that affects almost exclusively women. The main objectives of this study are to accurately evaluate the prevalence of LAM, the status of disease, the diagnosis and treatment, the quality of care, and the health related outcomes in China.

NCT ID: NCT01053182 Recruiting - Esophageal Cancer Clinical Trials

Esophagectomy Associated Respiratory Complications: Ivor-Lewis Versus Sweet Approaches

Start date: January 2010
Phase: Phase 3
Study type: Interventional

Worldwide, esophageal cancer is the 6th most common cause of cancer-related death. Currently curative resection remains the cornerstone of the therapy. Despite advances in anesthesia, operative techniques and postoperative management, postoperative pulmonary complications (PPCs) occur frequently accounting for about 30% of all postoperative complications. Most importantly, PPCs have much been associated with postoperative mortality. The diaphragm is the most important respiratory muscle and its respiratory function would be inevitably damaged when esophagectomy is performed through the left posterolateral thoracotomy (Sweet procedure) because the diaphragm must be dissected for the purpose of stomach moralization. Meanwhile, Ivor-Lewis approach may effectively avoid diaphragm injury because the stomach can be managed through a laparotomy whereas an additional abdomen incision is needed. Both procedures are routinely used in practice when surgically managing esophageal cancer. The investigators hypothesize that Ivor-Lewis procedure might be superior to the left-thoracotomy route during esophagectomy in preventing PPCs.