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Pulmonary Exacerbation clinical trials

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NCT ID: NCT00333385 Terminated - Cystic Fibrosis Clinical Trials

Continuous Versus Short Infusions of Ceftazidime in Cystic Fibrosis

Start date: October 2001
Phase: Phase 4
Study type: Interventional

The aim of this trial was to compare the safety and efficacy of courses of tobramycin and ceftazidime, administered intravenously as either thrice daily short infusions or 24 h continuous infusion, in cystic fibrosis patients with acute exacerbation of chronic pulmonary PA infection. In conventional treatment regimens, ceftazidime is administered in the form of thrice daily short infusions, but pharmacodynamic considerations suggest that continuous infusion could be more effective.