Effects of Standing at Different Angles on Transpulmonary Pressure

Status Not yet recruiting

Clinical Trial Summary

Effects of standing at different angles on transpulmonary pressure

Clinical Trial Description

Objective: To study the effect of different standing angles on cross-lung pressure.Background: Long-term bed rest in ICU patients leads to upward movement of diaphragm and increased intrathoracic pressure in mechanically ventilated patients, resulting in lower cross-lung pressure. If the end-expiratory cross-lung pressure is negative, lung tissue compression and atelectasis will occur.Standing can lower the diaphragm, improve the pressure across the lungs, and improve ventilation.Selection methods: patients with invasive mechanical ventilation in the ICU, on the premise of stable hemodynamics, with the aid of electric bed training in standing in different angles, start from 20 degrees, 5 degrees up every five minutes, the largest up to 80 degrees, each Angle across the pulmonary pressure, die cavity ratio, tidal volume and breathe out carbon dioxide at the end of the record, and record whether low blood pressure, an accident in the process of take off the tube and other adverse reactions. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04451421
Study type	Interventional
Source	Chinese PLA General Hospital
Contact	Zhao Ying
Phone	17600953801
Email	1412888703@qq.com
Status	Not yet recruiting
Phase	N/A
Start date	October 1, 2020
Completion date	October 1, 2021

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