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Clinical Trial Summary

The age of puberty has fluctuated throughout history. Recent data shows an increase in the age of onset of puberty signs, in the United States but also in Europe. A recent Public Health France study published in 2018 reports an increase in the incidence of precocious puberty with geographical heterogeneity. The consequences of these appearances include the early onset of menarche, short adult height and the psychological impact. Due to a lack of studies and additional data, the reasons for this development are difficult to understand. Among current hypotheses, the entanglement with the evolution of our environment is at the forefront: the action of environmental endocrine disruptors and nutritional factors could play a role in the process of early appearance of pubertal signs. The establishment of a national observatory for early and advanced puberty in collaboration with pediatric endocrinologists (on the front line) would allow a reliable and precise field approach, capable of supplementing epidemiological data, which are currently insufficient. The investigators hypothesize that the establishment of an observatory of pubertal advances (early puberty and advanced puberty) in private medicine is possible, with inclusion of at least 75% of eligible patients, and collection of at least 80% of data.


Clinical Trial Description

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Study Design


Related Conditions & MeSH terms


NCT number NCT06263868
Study type Observational
Source Hospices Civils de Lyon
Contact Emillie Doye, MD
Phone 0472118890
Email emilie.doye@chu-lyon.fr
Status Not yet recruiting
Phase
Start date March 1, 2024
Completion date March 1, 2028

See also
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Completed NCT00660010 - Study of Lupron Depot In The Treatment of Central Precocious Puberty Phase 3
Recruiting NCT04884620 - The 3rd COPENHAGEN Puberty Study
Active, not recruiting NCT03628937 - The Effect of Decaffeinated Green Tea Polyphenol Intake on the Risk of Precocious Puberty Among Obese Girls N/A
Enrolling by invitation NCT02790112 - Long-term Outcome of GnRH Analogues Treatment of Children With Idiopathic Central Precocious Puberty N/A