Neuroplasticity-oriented Cognitive Intervention in Early Onset and First Admission Schizophrenia

Psychosis Clinical Trial

Official title:

Neuroplasticity-oriented Cognitive Intervention in Early Onset and First Admission Schizophrenia

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01781364
• Other study ID #: FP16963311
• Status: Completed
• Phase: N/A
• First received: January 22, 2013
• Last updated: December 15, 2014
• Start date: January 2012
• Est. completion date: December 2014

Study information

• Verified date: December 2014
• Source: University of Konstanz
• Contact: n/a
• Is FDA regulated: No
• Health authority: Germany: University of Konstanz Ethics Committee
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to reveal the specific effects of computer-aided cognitive training on course and rehabilitation in early onset schizophrenia

Description:

Impairment in cognitive functions is one of the main symptoms in schizophrenia and is currently one of the challenges in the treatment of the disease. We examine the beneficial effect of computer-aided training program on course and rehabilitation of young psychotic patients with early onset psychosis. In addition we develop predictors for the course of disorder from neuroimaging data.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 20
• Est. completion date: December 2014
• Est. primary completion date: December 2014
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 17 Years to 37 Years

Eligibility

Inclusion Criteria:

• Early Onset Psychosis

Exclusion Criteria:

• Chronicity

• Insufficient German skills

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

• Psychosis

Intervention

Behavioral:
• Brain Fitness Training, Posit Science SF
Computer aided cognitive training based on principles of neuroplasticity

Locations

Country	Name	City	State
Germany	University Konstanz	Konstanz	Baden Wuerttemberg

Sponsors (1)

Lead Sponsor	Collaborator
University of Konstanz

Country where clinical trial is conducted

Germany, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	change from baseline at post-training and at 3-months and at 7-months follow-up in each of the following outcome measures: neuropsychological test performance (MCCCB), GAF, PANSS, MEG event-related potentials (M50), alpha activity		baseline, post-training (training duration 4 weeks), 3-month follow-up, 7-month follow-up	No
Secondary	change from baseline in GAF score at 3-months and 7-moths follow-up		baseline, 3-months follow-up, 7-months follow-up	No