Psychiatric Disorder Clinical Trial
— GLMwPDOfficial title:
A Randomized Controlled Study of Conservative Treatment of Granulomatous Lobular Mastitis Combined With Psychiatric Disorders
Verified date | May 2022 |
Source | Wuhan University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Granulomatous lobular mastitis (GLM) is a relatively rare chronic inflammatory disease of the breast in clinical practice. A small number of patients develop hyperprolactinemia during psychiatric drug treatment, and most of these patients are nulliparous. At present, there is no unified treatment mode at home and abroad, and surgery is generally the main treatment. GLM is a sterile inflammation, and glucocorticoids and methotrexate can effectively relieve clinical symptoms and even reach the standard of cure. In order to reduce the recurrence rate and protect the breast appearance as much as possible, we propose a conservative therapy. The purpose of this study was to compare this conservative therapy of granulomatous lobular mastitis with existing surgical treatment, and to compare the overall benefits of the two for patients with GLM. We aim to protect the breast appearance on the premise of low recurrence, improve the quality of life of GLM patients with psychiatric disorders .
Status | Enrolling by invitation |
Enrollment | 50 |
Est. completion date | January 30, 2027 |
Est. primary completion date | December 30, 2022 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 18 Years to 60 Years |
Eligibility | Inclusion Criteria: - Patients aged 18 years or older with granulomatous lobular mastitis - Patients with Psychiatric Disorders; - Patients volunteered to participate in the study after informed consent. Exclusion Criteria: - Patients were diagnosed with mastitis with other definite etiology confirmed by pathology - Patients in acute exacerbation of mental illness |
Country | Name | City | State |
---|---|---|---|
China | Zhongnan Hospital of Wuhan University | Wuhan | Hubei |
Lead Sponsor | Collaborator |
---|---|
Wuhan University |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Recurrence rate | Inflammatory changes, mass, abscess or fistula formation, nodular erythema of the upper and lower extremities and joint pain occurred in the ipilateral breast within one year after surgery was defined as recurrence. | Up to 1 years | |
Primary | Breast appearance and cosmetic effect score | Refer to Harris standard to evaluate postoperative cosmetic effect. Specify the breast appearance and cosmetic effect rating table. | Up to 1 years | |
Secondary | recovery time | the timing of the disappearance of the symptoms including Inflammatory changes, mass, abscess or fistula formation, nodular erythema of the upper and lower extremities and joint pain occurred in the ipilateral breast | Up to 2 years |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03409991 -
Testing the Efficacy of Opening Doors: A Career Guidance Intervention for Individuals With Psychiatric Disabilities
|
N/A | |
Not yet recruiting |
NCT05316948 -
Mental Health and Sexuality in Adolescents and Young Adults
|
||
Completed |
NCT04778163 -
The Use of Humor With Young Adults in Psychiatric Care
|
N/A | |
Not yet recruiting |
NCT06304363 -
Braining - Evaluation of Acute Effects of Physical Exercise
|
N/A | |
Recruiting |
NCT04096625 -
Enhancement of a Psychotherapeutic Intervention Through Transcranial Direct Current Stimulation (tDCS)
|
N/A | |
Terminated |
NCT06012981 -
Psychological Treatment in Psychiatric Inpatient Care
|
N/A | |
Not yet recruiting |
NCT05930353 -
Psychometric Validation of a French-language Version of the PERMA-Profiler: Tools for Assessing Multidimensional Subjective Well-being
|
||
Completed |
NCT04099173 -
A Brief Mindfulness-Based Intervention for Suicidal Ideation
|
N/A | |
Completed |
NCT01866956 -
Computerized Screening for Comorbidity in Adolescents With Substance or Psychiatric Disorders
|
||
Recruiting |
NCT04249960 -
Sustain and Reinforce the Transition From Child to Adult Mental Health Care in Switzerland : A Monocentric Nested Cohort Randomized Controlled Trial: The SORT Study.
|
N/A | |
Recruiting |
NCT05962424 -
HNC: Human Neural Circuits Electrophysiology During Cognition
|
Phase 1 | |
Recruiting |
NCT06092866 -
Digital Versus Telephone Symptom Assessment and Triage in Primary Care
|
N/A | |
Recruiting |
NCT03678194 -
Treating Depression on a Day-to-day Basis: Development of a Tool for Physicians Based on a Smartphone Application
|
N/A | |
Completed |
NCT03748355 -
Using Pharmacogenetics to Identify Patients With Polypharmacy at Risk of Medication Adverse Effects
|
N/A | |
Completed |
NCT05473962 -
Mid-Term Follow-up Assessment After Exposure to Natural Disaster
|
||
Recruiting |
NCT05577585 -
Ketamine and Stress in OCD
|
N/A | |
Completed |
NCT05124158 -
COVID-19 Severity and Psychiatric Morbidity
|
||
Recruiting |
NCT05560581 -
Digital Self-efficacy Training to Bridge Waiting Times for Psychotherapy
|
N/A | |
Completed |
NCT04618250 -
Improving Physical Health in Patients With Psychiatric Disorders in General Practice (SOFIA)
|
N/A | |
Not yet recruiting |
NCT06014164 -
Qualitative Study About Psychedelics Using in Psychiatric Disorders
|