Psoriasis Vulgaris Clinical Trial
Official title:
Predicting Inflammatory Skin Disease Response to IL-23 Blockade
Verified date | April 2024 |
Source | University of California, San Francisco |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This study examines the effect of IL-23 blockade with Tildrakizumab on the immune cells of psoriatic skin lesions.
Status | Completed |
Enrollment | 7 |
Est. completion date | January 15, 2023 |
Est. primary completion date | January 15, 2023 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Male or female =18 years of age at clinic visit. - Documentation of moderate-severe psoriasis or atypical psoriasis. - Written informed consent (and assent when applicable) obtained from subject or subject's legal representative and ability for subject to comply with the requirements of the study. Exclusion Criteria: - Presence of a condition or abnormality that in the opinion of the Investigator would compromise the safety of the patient or the quality of the data - Tuberculosis, active serious infection, active systemic malignancy, - Received a systemic medication for psoriasis within 3 months of study screening |
Country | Name | City | State |
---|---|---|---|
United States | University of California, San Francisco | San Francisco | California |
Lead Sponsor | Collaborator |
---|---|
University of California, San Francisco | Sun Pharmaceutical Industries Limited |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Psoriasis Area and Severity Index (PASI) Score | Psoriasis Area and Severity Index (PASI) is a measure of psoriasis severity. The maximum score is 72, minimum score is 0. The higher the number, the more severe the psoriasis is. | baseline and 3 months |
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