New Score for Pseudo- Acanthosis Nigricans

Pseudo Acanthosis Nigricans Clinical Trial

Official title:

Use Of A Novel Quantitative Tool For Evaluation of Pseudo- Acanthosis Nigricans: Acanthosis Nigricans Area And Severity Index

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT04359485
• Other study ID #: EgyANASI
• Status: Active, not recruiting
• Phase: N/A
• Start date: August 1, 2019
• Est. completion date: June 2020

Study information

• Verified date: April 2020
• Source: Kasr El Aini Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Each side of the neck pseudo acanthosis nigricans was randomized in to either receiving glycolic acid peel or saline. Evaluation was done at baseline and after 3 sessions 2 weeks apart by percentage involvement and by ANASI score

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 20
• Est. completion date: June 2020
• Est. primary completion date: November 1, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 60 Years

Eligibility

Inclusion Criteria:

• mild to moderate severity

• age > 18 years old

Exclusion Criteria:

• Pregnant and lactating patients,

• patients with systemic diseases as connective tissue disease, diabetes,

• skin infection

• use of immunosuppressive drugs

• Susceptibility for post peel hazards as hyperpigmentation

• scarring and keloidal tendency

Related Conditions & MeSH terms

• Acanthosis Nigricans
• Pseudo Acanthosis Nigricans

Intervention

Procedure:
• Glycolic acids peel 70%
Glycolic acid peel 70% applied in 3 coats medium depth

Other:
• Saline
Sodium chloride

Locations

Country	Name	City	State
Egypt	Kasr El Ainy university hospital, Faulty of medicine,Cairo university	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Kasr El Aini Hospital

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Percentage involvement	Degree of severity expressed as a percentage	6 months to 1 year
Primary	Acanthosis Nigricans Area and Severity Index score	New Score calculating severity and area as a number minimum value is 0 and maximum value is 40 the higher the number of the score the worse the affection	6 months to 1 year