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NCT01094327 Clinical Trial

Proteinuria in Pre and Post Transplant

Proteinuria Clinical Trial

Official title:
Evaluation of Recipients With and Without Proteinuria, Pre and Post Kidney Transplantation

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT01094327
Other study ID # 20070206
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date February 2008
Est. completion date December 2024

Study information
Verified date November 2023
Source University of Miami
Contact George Burke, M.D.
Phone 305-355-5111
Email gburke@med.miami.edu
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Patients with focal segmental glomerulosclerosis (FSGS) who progress rapidly to end stage renal disease (ESRD) are at highest risk for development of recurrence of proteinuria following kidney transplantation. This study will look at serum specimens pre and post transplant, as well as kidney transplant specimens pre and post reperfusion to identify where the defects has occured that results in recurrence of proteinuria in a given kidney transplant.

Description:

This study will retrospectively review patient's medical records for protein in the urine, blood creatinine and kidney biopsy results. Also character of the fluid used to flush the kidney before transplant will be analyzed.

Recruitment information / eligibility
Status Recruiting
Enrollment 100
Est. completion date December 2024
Est. primary completion date December 2024
Accepts healthy volunteers No
Gender All
Age group N/A to 25 Years
Eligibility Inclusion Criteria: - Kidney transplant recipients - Pediatric males and females up to the age of 25 years old. Exclusion Criteria: - Transplant recipients other than kidney

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
United States University of Miami Miller School of Medicine Transplant Clinic Miami Florida

Sponsors (1)
Lead Sponsor Collaborator
University of Miami

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Explain mechanisms behind the development of proteinuria in patients immediately after receiving a kidney transplant chart review through study completion, an average of 5 years
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