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Clinical Trial Summary

In rodents with protein C deficiency elevated levels of ghrelin has been observed. The purpose of this study is to investigate if patients with protein C deficiency also have elevated levels of ghrelin, and if so, how this affects the patients.

30 patients with protein C deficiency and 30 healthy BMI and gender matched controls are recruited. Bloodsamples are taken in order to measure ghrelin and GH levels and other metabolic parameters. The patients and controls are also asked to answer a questionaire regarding appetite.

If patients with protein C deficiency have higher levels of ghrelin than the general population, this will lead to new studies that will perhaps help us understand the importance of ghrelin in humans.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04180657
Study type Observational
Source University of Aarhus
Contact Sascha S Horup, MD
Phone +45 27149089
Email SASHOR@rm.dk
Status Not yet recruiting
Phase
Start date January 2020
Completion date July 2020

See also
  Status Clinical Trial Phase
Completed NCT01127529 - Ceprotin Treatment Registry
Completed NCT00161720 - Retrospective Study to Capture Dosing and Treatment Outcome Data in Participants With Severe Congenital Protein C Deficiency Who Were Treated With Protein C Concentrate Under an Emergency Use IND
Completed NCT00157118 - Efficacy and Safety Study of Protein C Concentrate in Subjects With Severe Congenital Protein C Deficiency Phase 2/Phase 3