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NCT04746001 Clinical Trial

Artificial Intelligence in the Diagnosis of Orthopaedic Conditions, Particularly Bone Tumours and Infection

Prosthetic Joint Infection Clinical Trial

— AIortho  

Official title:
Artificial Intelligence in the Diagnosis of Orthopaedic Conditions, Particularly Bone Tumours and Infection

Clinical Trial Details — Status: Enrolling by invitation

Administrative data
NCT number NCT04746001
Other study ID # 281854_47208_2021
Secondary ID
Status Enrolling by invitation
Phase
First received
Last updated
Start date June 28, 2021
Est. completion date July 1, 2024

Study information
Verified date November 2021
Source Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Translational research aimed at improving diagnostic accuracy of musculoskeletal infection and musculoskeletal tumours using machine learning applied to clinical data, histopathological sections and genomic sequencing.

Recruitment information / eligibility
Status Enrolling by invitation
Enrollment 100
Est. completion date July 1, 2024
Est. primary completion date January 1, 2024
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: Suspected infection of bone tumour and biopsy taken for analysis Exclusion Criteria: Patient doesn't consent

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• Genomic sequencing
Sequencing data
• Histological examination
Images for deep learning

Locations
Country Name City State
United Kingdom Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Trust Oswestry Shropsire

Sponsors (2)
Lead Sponsor Collaborator
Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust Keele University

Country where clinical trial is conducted

United Kingdom, 

Outcome
Type Measure Description Time frame Safety issue
Primary Sequencing data and identification Identification of infection and tumours using sequencing data 3 years
Primary Histological slides and identification Deep learning using histological images 3 years
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