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Prosthesis and Bone Infections clinical trials

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NCT ID: NCT03950063 Not yet recruiting - Cutibacterium Acnes Clinical Trials

Cutibacterium Acnes in Bone and Joint Infections

CaBJI
Start date: June 15, 2019
Phase:
Study type: Observational

Prosthetic Joint Infections (PJIs) are increasing with the use of orthopedic devices on an ageing population. Cutibacterium acnes is a commensal organism that plays an important role in the ecosystem healthy human skin, yet this species is also recognized as a pathogen in foreign body infection: endocarditis, prostatitis and specifically in PJIs. C. acnes is able to escape the immune system. This phenomenon could reflect two bacterial behavior: the bacterial internalization by host cells and the biofilm formation.