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Prostatitis clinical trials

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NCT ID: NCT03720951 Recruiting - Prostatitis Clinical Trials

Applying Pulsed Radiofrequency to the Pudendal Nerve Bilaterally Vs Its Application to Sacral Nerve Roots S2,3 and 4 Bilaterally in Chronic Prostatitis

Start date: November 1, 2018
Phase: N/A
Study type: Interventional

Prevalence estimates show that prostatitis is one of the most common urological conditions and that symptoms range considerably among men of various socioeconomic status, race, and age. For men under 50 years, prostatitis is the most common urologic outpatient diagnosis. Chronic prostatitis/chronic pelvic pain syndrome has high prevalence estimates internationally ( 16% North America, 14% Asian & Europeans). Men suffering from Chronic prostatitis/chronic pelvic pain syndrome report significant impairment in their quality of life which is also associated with greater health care expenditures.

NCT ID: NCT03641807 Recruiting - Clinical trials for Chronic Pelvic Pain Syndrome

Different Modes of Assessment on Acupuncture Effect on Patients With Chronic Prostatitis/Chronic Pelvic Pain Syndrome

Start date: November 1, 2018
Phase: N/A
Study type: Interventional

Background: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common disorder. Some studies have indicated that acupuncture may ameliorate the symptoms of CP/CPPS. However, results are varied and range widely, perhaps due to different modes of assessment including timepoints, places of assessment, and especially subjective scales. We propose to determine the efficacy of acupuncture relative to sham acupuncture for patients with CP/CPPS, and compare different modes of assessment regarding the therapeutic effects of acupuncture. Methods: Sixty patients with CP/CPPS will be randomly assigned to receive either acupuncture or sham-acupuncture (30 patients, each). Treatment will be conducted 3 times/week, for 4 weeks. The primary outcomes will each be the change from baseline of the total NIH (National Institutes of Health) CPSI (Chronic Prostatitis Symptom Index) score associated with 3 modes of assessment: Mode 1, the scale recorded at the hospital within 10minutes after the last session of 4 weeks of acupuncture treatment, in the company of the outcome assessors; Mode 2, the scale recorded the same day, but not at the hospital; and Mode 3, the scale recorded at the hospital 1 to 3 days after the last acupuncture session. The 3 key secondary outcomes include will be the 3 modes assessment of the changes from baseline of the NIH-CPSI total scores in the acupuncture group at week 4 after treatment. Analysis was by intention-to-treat, and multiplicity was controlled for with a step-down closed-testing procedure.

NCT ID: NCT03629769 Recruiting - Clinical trials for Premature Ejaculation

Effects of Proxelan Somministration in Patients With Chronic Prostatitis

Start date: February 16, 2017
Phase: Phase 3
Study type: Interventional

The purpose of the study is to determinate the antinflammatory effects of the Proxelan on a cohort of patients affected by prostatitis'like symptoms and clinical evidence of abacterical prostatistis, trough a significative improvements of pain symptoms according to the NIH-CPSI questionnaire items, spermatozoa motility/concentration variations and the semen cytokines level decrease.

NCT ID: NCT03543761 Completed - Chronic Prostatitis Clinical Trials

Low-intensity Shockwave Therapy for Non-bacterial Prostatitis/Pelvic Pain Syndrome

Start date: June 11, 2018
Phase: N/A
Study type: Interventional

The aim of the study is to investigate and compare the treatment efficacy and safety of ESWT vs sham treatment for CP/CPPS patients.This is a triple-blind, randomized, parallel group sham-controlled clinical study.

NCT ID: NCT03500159 Terminated - Clinical trials for Chronic Pelvic Pain Syndrome

Efficacy and Safety of AQX-1125 in Subjects With Chronic Prostatitis/Chronic Pelvic Pain Syndrome

CP/CPPS
Start date: April 18, 2018
Phase: Phase 2
Study type: Interventional

This is a randomized, multi-center, double-blind, parallel-group study, enrolling approximately 100 male subjects diagnosed with CP/CPPS to evaluate the effect of 12-week treatment with AQX-1125 (active drug) compared to placebo. The subjects will be randomized to receive orally once-daily either AQX-1125 (200 mg) or placebo in a 1:1 ratio across approximately 30 centers in North America (United States and Canada). The study will consist of a screening period of up to 3 weeks, a 12-week treatment period followed by a 4-week off drug safety follow-up period, and an ophthalmic safety follow-up call at 3 months and visit at 6 months post last dose, for a total study duration of about 41 weeks.

NCT ID: NCT03461263 Completed - Clinical trials for Chronic Non-bacterial Prostatitis

Effect of Pumpkin Seeds Phonophoresis on Chronic Non-bacterial Prostatitis

Start date: January 5, 2017
Phase: N/A
Study type: Interventional

It has been observed that out of all visits to the clinics by the young and middle age men for grievances including the genital and urinary frameworks, about 25% of the visits account for Prostatitis. A significant number of men, aged less than 50, visits to urologist due to Interminable prostatitis. Nevertheless, just 5 to10% of "prostatitis" cases is really caused by a bacterial contamination. The purpose was to investigate thoroughly the effect of pumpkin seeds oil phonophoresis among males who are diagnosed with chronic non-bacterial prostatitis.

NCT ID: NCT03213938 Completed - Clinical trials for Chronic Prostatitis With Chronic Pelvic Pain Syndrome

Acupuncture for Chronic Prostatitis/Chronic Pelvic Pain Syndrome

Start date: October 9, 2017
Phase: N/A
Study type: Interventional

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) refers to the presence of bothersome pelvic pain symptoms without an identifiable cause. Common symptoms of CP/CPPS include discomfort in the perineum, suprapubic region, and lower urinary tract symptoms. It affects men of all ages without apparent racial predisposition, among which, 36-50 years old are the most commonly influenced. Yet, few effective therapies are available for treating CP/CPPS. Acupuncture may be an effective treatment option for CP/CPPS. However, effects of acupuncture on CP/CPPS remain uncertain because of the small sample sizes or other methodological limitations. The objective of this multi-centre, randomized, sham acupuncture-controlled trial is to assess the effectiveness of acupuncture for relieving symptoms of CP/CPPS. The results will provide a robust conclusion with a high level of evidence.

NCT ID: NCT03201796 Completed - Clinical trials for Chronic Bacterial Prostatitis

Prulifloxacin in Chronic Bacterial Prostatitis (CBP)

Start date: February 2, 2016
Phase: Phase 2
Study type: Interventional

The aim of the study is to assess the efficacy and safety of prulifloxacin in comparison to levofloxacin in the treatment of patients affected by CBP.

NCT ID: NCT03167216 Completed - Clinical trials for Chronic Prostatitis With Chronic Pelvic Pain Syndrome

Mast Cells in Male Pelvic Pain and and Lower Urinary Tract Dysfunction

Start date: August 1, 2017
Phase: Early Phase 1
Study type: Interventional

The objective of this study is to evaluate inhibition of mast cells and the histamine 1 receptor (H1R) for treatment of chronic prostatitis (CP) and chronic pelvic pain syndrome (CPPS).

NCT ID: NCT03027076 Withdrawn - Clinical trials for Interstitial Cystitis

Microbiome of Urologic Chronic Pelvic Pain Syndrome

Start date: November 2013
Phase: N/A
Study type: Observational [Patient Registry]

This research is being done to learn more about the bacteria that live in the genito-urinary tract in subjects with urologic chronic pelvic pain syndrome (UCPPS).