Prostatic Neoplasm Clinical Trial
Official title:
Trimodal (18)F-choline-PET/mpMRI/TRUS Targeted Prostate Biopsies in Prostate Cancer Patients
Prostate cancer is the first cancer in humans (25%). The most widely used tracer in
oncology, the 18-Fluoro DeoxyGlucose does not allow the study of prostatic neoplasia. On the
other hand, Choline, which is an amino alcohol, is involved in the synthesis of cell
membranes and has an affinity for prostate cells. Its concentration is directly proportional
to cell proliferation. The analogue of choline has the advantage of having a rapid and
stable accumulation over time in cancer cells, with a rapid urinary excretion (4 minutes
after injection).
The goal of this study is to assess the feasibility and the accuracy for targeting image
guided prostate biopsy to detect prostate cancer after Imaging fusion of choline-PET/CT
compared to 1.5T multiparametric magnetic resonance imaging (mpMRI) with 3D-transrectal
ultrasound (TRUS) .
n/a
Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic
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