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Prostatic Hyperplasia clinical trials

View clinical trials related to Prostatic Hyperplasia.

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NCT ID: NCT05551221 Recruiting - Clinical trials for Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms

The Efficacy and Safety of Silodosin Singly or Combined With Ningmitai Capsules in the Treatment of Benign Prostatic Hyperplasia

NQTIPS
Start date: July 18, 2022
Phase: Phase 4
Study type: Interventional

Objective: To evaluate the efficacy and safety of Ningmitai Capsules and Silodosin Capsules in the treatment of Benign Prostatic Hyperplasia (BPH) with Lower Urinary Tract Symptoms (LUTS) compared with Tamsulosin Hydrochloride Sustained Release Capsules. Study design: A multicenter, prospective, randomized, double-blind, positive controlled clinical study. Interventions: Group A: Oral Tamsulosin Hydrochloride Capsules and Ningmitai Capsules placebo for 12 weeks. Group B: Oral l Silodosin Capsules and Ningmitai Capsules placebo for 12 weeks. Group C: Oral l Silodosin Capsules and Ningmitai Capsules for 12 weeks.

NCT ID: NCT05543200 Recruiting - Clinical trials for Benign Prostatic Hyperplasia

BPH Global Registry

Start date: March 13, 2023
Phase:
Study type: Observational [Patient Registry]

Benign prostatic hyperplasia (BPH) is one of the most common performed surgical procedures in urology. Over the past few decades there have been an increasing development of newer surgical treatment options. Additionally, the outcome parameters for BPH treatments have been standardized. While data are available for the initial pivotal studies, post-market release data are lacking. Under the umbrella of uCARE, we have started a prospective, ongoing international registry for recording demographics and outcomes for patients undergoing surgical treatments for BPH.

NCT ID: NCT05531240 Recruiting - Clinical trials for Prostate Hyperplasia

Transurethral Prostate Resection (TURP) vs. Prostate Artery Embolization (PAE)

Start date: October 2022
Phase: N/A
Study type: Interventional

This study focuses on the treatment of benign prostatic hyperplasia which causes lower urinary tract symptoms. The purpose of the research project is to evaluate PAE in terms of both medical and health economic outcomes. To evaluate whether there are any differences in effect (IPSS), complications, costs and perceived quality of life compared with TUR-P.

NCT ID: NCT05443451 Recruiting - Clinical trials for Prostate Hyperplasia

BETTY: BEnign Prostatic Hyperplasia Transperineal Targeted Microwave therapY

Start date: September 8, 2022
Phase: N/A
Study type: Interventional

This is a pilot study on applying 3D-Ultrasound-Guided Transperineal Microwave needle ablation for men with symptomatic benign prostatic hyperplasia (BPH).

NCT ID: NCT05440981 Recruiting - Clinical trials for Prostate Hyperplasia

Implanted Nitinol Device (iTind) System in Chinese Males With Lower Urinary Tract Symptom Secondary to BPH

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

This is a prospective series of consecutive cases of patients undergoing iTind for the treatment of male LUTS.

NCT ID: NCT05400980 Recruiting - Clinical trials for Benign Prostatic Hyperplasia

The Expander-2 Trial: A Randomized Study to Evaluate the Safety and Efficacy of the Urocross(TM) Expander System and Retrieval Sheath

Start date: July 5, 2022
Phase: N/A
Study type: Interventional

To demonstrate the safety and efficacy of the Urocross Expander System/Retrieval Sheath and the procedure to treat patients with symptomatic Benign Prostatic Hyperplasia (BPH).

NCT ID: NCT05341661 Recruiting - Clinical trials for Lower Urinary Tract Symptoms (LUTS)

Butterfly Pivotal Study

Start date: April 7, 2022
Phase: N/A
Study type: Interventional

A prospective, multicenter, blind randomized (2:1) controlled study comparing the International Prostate Symptom Score (IPSS) of the Active arm to the IPSS of the control arm at the 3 months follow-up and active arm IPSS score change from time zero to 12 months. Patients in the active arm undergo Butterfly device treatment. Patients in the control arm undergo a sham rigid cystoscopy procedure

NCT ID: NCT05330520 Recruiting - BPH Clinical Trials

Long Term Safety and Efficacy of Butterfly Medical Prostatic Retraction Device in Benign Prostatic Hyperplasia (BPH) Patients Who Completed 12 Months of Follow-Up Post Implantation (Continuation Study for Study BM-011-IL)

Start date: February 10, 2021
Phase: N/A
Study type: Interventional

This study evaluates the long term safety and efficacy of use of the Butterfly Medical's prostatic retraction device in Benign Prostatic Hyperplasia (BPH) Patients. The study follows patients implanted with the Butterfly device for up to 5 year after implantation. The evaluations include recording of safety events and BPH related symptoms by Uroflowmetry tests, residual urine and International Prostate Symptom Score (IPSS) questionnaires. The study also assesses the sexual quality of life after implantation of the Butterfly device.

NCT ID: NCT05292235 Recruiting - Clinical trials for Benign Prostatic Hyperplasia

Perioperative Parameter and Treatment Outcomes of Surgical Treatment for Benign Prostate Hyperplasia in Hong Kong

Start date: April 1, 2022
Phase:
Study type: Observational [Patient Registry]

This is a prospective data registry to assess the treatment outcomes and complications of different treatment approaches in our hospital clusters.

NCT ID: NCT05240001 Recruiting - Clinical trials for Benign Prostatic Hyperplasia

Thulium Fiber Laser (TFL) vs Holmium MOSES for Treatment of Benign Prostatic Hyperplasia (BPH)

Start date: April 20, 2022
Phase: N/A
Study type: Interventional

Benign prostatic hyperplasia (BPH), the non-cancerous enlargement of the prostate, places pressure on the urethra and causes urination and bladder problems. Transurethral Resection of the Prostate (TURP) remains the gold standard treatment in most centres for BPH. However, morbidity after TURP is high, especially bleeding requiring blood transfusion and late postoperative bleeding. Holmium laser enucleation of the prostate (HoLEP) is a safe and effective procedure which has demonstrated comparable results to TURP. HOLEP also offers patients the alternative of being treated endoscopically with minimal blood loss, short catheterization time, and decreased hospital stay. The main reason HoLEP has yet to become the new standard for treatment of symptomatic BPH is due the complexity of this procedure as compared to TURP. Furthermore, the HoLEP can be used with the MOSESTM system, a system that allows for more efficiency and ease of use of the HoLEP. Thulium fiber laser (TFL) enucleation of the prostate is an emerging technology for endoscopic prostate enucleation that is notable for its high wavelength and pulsed mode of action. Recent studies have shown TFL enucleation of the prostate to be a safe and highly efficacious treatment modality for the management of large volume (> 80 cm3) glands in BPH. Due to its novelty, further studies are needed to broaden the investigators' understanding of the TFL and comprehend the full implications and benefits of this new technology, as well its limitations. The aim of this study is to whether Thulium Fiber laser enucleation of the prostate (ThuFLEP) and Holmium laser enucleation using MOSES™ (M-HoLEP) have comparable length of hospital stay, as well as intraoperative and postoperative outcomes.