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Prostatic Hyperplasia clinical trials

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NCT ID: NCT00651807 Terminated - Clinical trials for Benign Prostatic Hyperplasia (BPH)

A Trial to Investigate the Effectiveness and Safety of Org 3236 (Etonogestrel) Tablets in Men With Urinary Complaints Suggestive of a Benign Enlargement of the Prostate (304001)(P05806)

Start date: March 2008
Phase: Phase 2
Study type: Interventional

This trial is conducted to evaluate the effect of etonogestrel in comparison to placebo on: - the prostate volume and the urinary complaints; - the urinary flow and the urinary volume in the bladder after voiding; - the progression of the disease; - the sexual function, well-being and urinary complaints-related Quality of Life. In addition the safety and the way the drug is absorbed and excreted by the body will be analyzed.

NCT ID: NCT00563654 Terminated - Clinical trials for Prostatic Hyperplasia

Randomized Trial Comparing Alfuzosin GITS 10 mg Daily With Placebo for Trial Without Catheter in Acute Urinary Retention With Long Term Follow up

Start date: October 2005
Phase: N/A
Study type: Interventional

The purpose of the study is to compare alfuzosin GITS once daily versus placebo in achieving a successful TWOC after AUR due to BPH, among Chinese males in Hong Kong, and in delaying or avoiding a TURP.

NCT ID: NCT00563485 Terminated - Clinical trials for Prostatic Hyperplasia

Randomized Trial Comparing Terazosin 5 mg Daily and Doxazosin GITS 4 mg Daily for Trial Without Catheter in Acute Urinary Retention With Long Term Follow up

Start date: October 2005
Phase: N/A
Study type: Interventional

The purpose of the study is to compare two alpha blockers, terazosin and doxazosin GITS, in achieving a successful TWOC after AUR due to BPH, among Chinese males in Hong Kong, and in delaying or avoiding a TURP.

NCT ID: NCT00501371 Terminated - Clinical trials for Benign Prostatic Hyperplasia

MCS in Treating Lower Urinary Tract Symptoms (LUTS) Suggestive of Benign Prostatic Hyperplasia

Start date: July 2007
Phase: Phase 3
Study type: Interventional

Phase III, Randomized, double-blind, parallel placebo-controlled study. Two arms: MCS (30mg/day) vs. placebo. Subproject MCS-2: alpha-blocker naïve subjects Subproject MCS-3: subjects responding poorly to alpha-blocker

NCT ID: NCT00454402 Terminated - Clinical trials for Prostatic Hyperplasia

ALF-STONE: Alfuzosin in Uretheric Stones

Start date: August 2006
Phase: Phase 3
Study type: Interventional

The aim of the study is to assess the effect of Alfuzosin compared with placebo, for 7 days, on the outcome of patients with uretheric stones submitted to Extracorporeal Shock Wave Lithotripsy (ESWL), namely in the percentage of patients without imagiologic evidence of any stone after 72h to 96 hours. This study will also specifically focus on the evaluation of time of stone clearance and of pain reduction (Numeric Rating Scale).

NCT ID: NCT00449150 Terminated - Clinical trials for Benign Prostatic Hypertrophy

Cetrorelix (CET) Pamoate Regimens in Patients With Symptomatic Benign Prostatic Hypertrophy (BPH)

Start date: March 2007
Phase: Phase 3
Study type: Interventional

Benign Prostatic Hypertrophy (BPH) is a common and bothersome condition of aging men. It is characterized by an enlargement of the prostate occurring in human male over the age of 50 which increases in prevalence with age, and among those aged 50 to 80, about 40% report moderate or severe urinary symptoms of prostatism. The aim of treatment is to improve patients' quality of life which primarily depends on the severity of the symptoms of BPH. Current treatments of BPH have a benefit / risk ratio which leaves room for improvement. For this study, study medication (Cetrorelix pamoate or placebo) is administered by injection in the buttocks (Intramuscular). All patients completing the double-blind portion (Week 0 to 52) are eligible to receive the active drug during the open-label part of the study (Week 52 to 90).

NCT ID: NCT00435448 Terminated - Clinical trials for Benign Prostatic Hyperplasia

Study of the Efficacy and Safety of Lonidamine for the Treatment of Symptomatic Benign Prostatic Hyperplasia

Start date: June 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy of lonidamine (50mg, 150mg) compared to placebo in subjects with symptomatic BPH.

NCT ID: NCT00431626 Terminated - Clinical trials for Benign Prostatic Hyperplasia

A Clinical Trial Comparing Laser TURP With and Without Dutasteride.

Start date: October 2006
Phase: Phase 3
Study type: Interventional

The purpose of this research study is to determine if the study drug Dutasteride taken before and after Laser TURP(Transurethral Resection of the Prostate), can provide effective and safe, long term improvement of lower urinary tract symptoms.

NCT ID: NCT00421421 Terminated - Clinical trials for Benign Prostatic Hyperplasia

Effects Of Dutasteride On Risk Reduction Of Acute Urinary Retention Relapse Following Trial Without Catheter

Start date: March 2007
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of dutasteride at reducing relapse rates of Acute Urinary Retention (AUR), including reduction in surgical intervention for benign prostatic hyperplasia (BPH), in patients who receive a 6 month treatment of dutasteride (0.5mg once daily) following a single episode of AUR followed by successful Trial Without Catheter compared with placebo.

NCT ID: NCT00237536 Terminated - Clinical trials for Benign Prostatic Hyperplasia

Study of the Efficacy and Safety of Lonidamine for the Treatment of Symptomatic Benign Prostatic Hyperplasia

Start date: June 2005
Phase: Phase 2
Study type: Interventional

The purpose of this trial is to evaluate the dose response relationship of lonidamine and the primary efficacy endpoint, International Prostate Symptom Score (IPSS), in subjects with symptomatic benign prostatic hyperplasia (BPH).