Effect of Adding Sufentanil to Epidural Ropivacaine on Perioperative Metabolic and Stress Responses in Combined General/Epidural Anaesthesia for Geriatric Radical Retropubic Prostatectomy

Prostatic Cancer Clinical Trial

Official title:

Effect of Adding Sufentanil to Epidural Ropivacaine on Perioperative Metabolic and Stress Responses in Combined General/Epidural Anaesthesia for Geriatric Radical Retropubic Prostatectomy

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01086956
• Other study ID #: 4-2008-0319
• Status: Completed
• Phase: N/A
• First received: March 12, 2010
• Last updated: November 10, 2010
• Start date: September 2008
• Est. completion date: December 2009

Study information

• Verified date: November 2010
• Source: Yonsei University
• Contact: n/a
• Is FDA regulated: No
• Health authority: Korea: Food and Drug Administration
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to compare metabolic and stress responses in combined general/epidural anesthesia in geriatric cancer patients.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: December 2009
• Est. primary completion date: December 2009
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 65 Years and older

Eligibility

Inclusion Criteria:

• elective RRP for prostatic cancer scheduled in the morning (9-11 a.m.)

• patients aged more than 65 years

• ASA physical status I or II

• absence of contraindications to epidural approach

• absence of a history of chronic pain or opioid medication

Exclusion Criteria:

• contraindication to epidural catheterization

Study Design

Allocation: Randomized, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

• Prostatic Cancer
• Prostatic Neoplasms

Intervention

Drug:
• epidural infusion of saline, ropivecaine, or ropivacaine and sufentanil

Locations

Country	Name	City	State
Korea, Republic of	Severance Hospital	Seoul

Sponsors (1)

Lead Sponsor	Collaborator
Yonsei University

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	plasma glucose, insulin, cortisol, epinephrine, norepinephrine, prolactin		from preoperative baseline to postoperative 24 hours	No