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Comparison of Plasma Neutrophil Gelatinase - Associated Lipocalin (NGAL) Levels

Prostatectomy Clinical Trial

Official title:
Comparison of Plasma Neutrophil Gelatinase - Associated Lipocalin (NGAL) Levels After Robot-assisted Laparoscopic Versus Retropubic Radical Prostatectomy

Clinical Trial Summary

The purpose of the study is to compare the effect of two surgical techniques (open vs robotic assisted) on plasma levels of NGAL (neutrophil gelatinase-associated lipocalin) after radical prostatectomy.

Clinical Trial Description

Patients undergoing radical prostatectomy are at increased risk of acute kidney injury (AKI) because of intraoperative bleeding, obstructive uropathy and older age. In particular robot-assisted laparoscopic radical prostatectomy (RALP) which is in increasing demand as an alternative surgical option for retropubic radical prostatectomy (RRP) is associated with postoperative renal dysfunction because pneumoperitoneum during RALP can decrease cardiac output and renal perfusion. NGAL may become important for diagnosis of postoperative AKI after urogenital oncosurgery. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03607279
Study type Observational [Patient Registry]
Source Antalya Training and Research Hospital
Contact
Status Completed
Phase
Start date January 2017
Completion date August 2017
View Details
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