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Clinical Trial Summary

This will be a prospective cohort trial that compares transperineal to transrectal MRI-US fusion prostate biopsy


Clinical Trial Description

This will be a prospective cohort trial that compares transperineal to transrectal MRI-US fusion prostate biopsy among men. The target population are males that are schedule to undergo MRI-US Fusion prostate biopsy and have an MRI of the prostate. All the pathological samples would be conducted from the area in the prostate that was found as suspicious of malignancy by previous MRI imaging, and defined as region of interest (ROI).

First the prostate biopsy will be preformed in a transperineal approach; Then a transrectal approach would be used to sample a few more cores.

The primary endpoint will be To compare the detection rate for clinically significant prostate cancer between transperineal vs transrectal mp-MRI-fusion/TRUS biopsies. Additionally, the study aims to determine the accuracy of prostate cancer detection in transperineal vs transrectal mp-MRI-fusion/TRUS biopsies. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03413137
Study type Interventional
Source Rabin Medical Center
Contact Sivan Sela, B.Sc
Phone +972(0)3-9376553
Email Sivanto1@clalit.org.il
Status Recruiting
Phase N/A
Start date December 11, 2017
Completion date October 2019

See also
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Completed NCT03040050 - Rapid PCR to Guide Antibiotic Therapy at the Time of Prostate Biopsy N/A
Completed NCT03500432 - A Study of a New Local Anesthesia Method for Transperineal Prostate Biopsy N/A
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Not yet recruiting NCT06183905 - Multi-parametric Ultrasound Versus Multi-parametric MRI for Prostate Cancer Detection N/A
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