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Combination of Entinostat and Enzalutamide in Advanced Prostate Cancer

Prostate Adenocarcinoma Clinical Trial

Official title:
A Phase I Study of Entinostat in Combination With Enzalutamide for Treatment of Patients With Castration-Resistant Prostate Cancer

Clinical Trial Summary

To determine the safety and tolerability of Entinostat in combination with Enzalutamide in metastatic castrate resistant prostate cancer

Clinical Trial Description

This study is designed to determine the safety and tolerability of Entinostat with Enzalutamide for treatment of patients with castration-resistant prostate cancer. There will be two dose levels of Entinostat in combination with same dose of Enzalutamide. Patients will be followed during treatment and 1 month post discontinuation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03829930
Study type Interventional
Source George Washington University
Contact
Status Terminated
Phase Phase 1
Start date May 1, 2019
Completion date September 1, 2020
View Details
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