General Anesthesia Clinical Trial
Official title:
Electroencephalographic Profiles During General Anesthesia: a Comparative Study of Remimazolam and Propofol
How anesthetic drugs induce and maintain the behavioral state of general anesthesia is an important question in medicine and neuroscience. Different anesthetic drugs act on different molecular targets and neural circuit mechanisms, exhibiting drug-specific EEG features. As a novel ultra-short-acting benzodiazepines drugs, remimazolam has been accepted for induction and maintenance of clinical anesthesia. Compared to the traditional benzodiazepines drugs, remimazolam combines the safety of midazolam with the effectiveness of propofol, and also has the advantages of acting quickly, short half-life, no injection pain, slight respiratory depression, independent of liver and kidney metabolism, long-term infusion without accumulation, and has a specific antagonist: flumazenil. This study aimed to investigate the differences in the characteristics of EEG oscillations during general anesthesia by comparing propofol and remimazolam.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT04577430 -
Effects of Dexmedetomidine on Cardiac Electrophysiology in Patients Under General Anesthesia During Perioperative Period
|
N/A | |
| Completed |
NCT03708692 -
Menstrual Cycle Phases on Recovery and Cognitive Function
|
||
| Recruiting |
NCT03422315 -
Population Pharmacokinetics and Clinical Individual Dosage Regimen of Propofoll Injection
|
N/A | |
| Completed |
NCT02771067 -
The Utility of Pulse Pressure Variation to Predict the Fluid Responsiveness During Pneumoperitoneum and Reverse-Trendelenburg Position
|
N/A | |
| Completed |
NCT05063461 -
Evaluation of the Analgesia Nociception Index With Varying Remifentanil Concentrations Under Sevoflurane
|
N/A | |
| Completed |
NCT03294226 -
Comparison of AuraGain With I-gel for Pediatric Patients
|
N/A | |
| Not yet recruiting |
NCT03643029 -
The Accuracy of the Performance and Placement Test for Predicting Supraglottic Airway Device (SAD) Position in the Hypopharynx as Confirmed With Video Laryngoscopy
|
N/A | |
| Completed |
NCT01945411 -
Assessment of Facial Measurements, the Length of Mouth Corner-mandible Angle and Incisors-mandible Angle, for Determining the Proper Sizes of Oropharyngeal Airway
|
N/A | |
| Not yet recruiting |
NCT01678066 -
A Prospective Study to Bilaterally Compare a Non-Invasive Cardiac Output Monitor
|
N/A | |
| Completed |
NCT01705743 -
Minimum Alveolar Concentration of Sevoflurane With Nitrous Oxide Inducing Isoelectric EEG
|
Phase 4 | |
| Completed |
NCT00972491 -
The Optimal Time to Put Laryngeal Mask Airway in the Mouth Under General Anesthesia
|
N/A | |
| Completed |
NCT01096212 -
Efficacy and Safety of Sevofran in Patients Scheduled for Elective Surgery Under General Anesthesia
|
Phase 4 | |
| Completed |
NCT00741507 -
Unhealthy Alcohol Drinking and Anesthetic Requirement in Women
|
N/A | |
| Completed |
NCT00532402 -
Continuous and Discontinuous Determination of Propofol Concentration in Breathing Gas
|
N/A | |
| Completed |
NCT00599066 -
Intraoperative M-Entropy Measurements
|
N/A | |
| Completed |
NCT00468494 -
Can Blood Glucose Levels During the Perioperative Period Identify a Population at Risk for Hyperglycemia?
|
N/A | |
| Recruiting |
NCT00492453 -
Spinal Versus General Anesthesia for Laparoscopic Cholecystectomy
|
N/A | |
| Recruiting |
NCT03745079 -
Correlation Between Core Temperature and Skin Temperature Measured by 3M SpotOn
|
||
| Completed |
NCT04094376 -
Comparison of Morning Operation and Evening Operation on Postoperative Sleep Quality and Pain Under General Anesthesia
|
N/A | |
| Enrolling by invitation |
NCT03672734 -
Volume and pH of Gastric Contents in Patients Undergoing Gynecologic Laparoscopic Surgery During Emergence From General Anesthesia
|