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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT04431557
Other study ID # 201509018RINB
Secondary ID
Status Completed
Phase
First received
Last updated
Start date July 19, 2017
Est. completion date February 19, 2019

Study information

Verified date July 2017
Source National Taiwan University Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The investigators will record 120 patients who received general anesthesia, their EEG data recorded from Bispectral Index (BIS) machine for emperical mode decomposition (EMD) analysis, the investigators decomposed EEG signal to different oscillations and tried to observe the differences between hypnotic medications through EEG analysis.


Description:

The electroencephalography (EEG) is a noninvasive medical technique for monitoring and recording the electrical activity of brain. The Hilbert-Huang transform (HHT) was proposed to decompose EEG signal into intrinsic mode functions (IMF) which can obtain instantaneous frequency data and work well for data that is nonstationary and nonlinear.

The relationship between frontal EEG patterns and hypnotics remain poorly understood. The investigators only can tell the increase in frontal EEG power and shift power to lower frequencies during general anesthesia from publications. The investigators are going to decompose EEG with HHT and find the energy shift during general anesthesia, compare with different anesthetics.

The investigators will record 120 patients who received general anesthesia, their EEG data recorded from BIS machine for EMD analysis, the investigators decomposed EEG signal to different oscillations and tried to observe the differences between hypnotic medications through EEG analysis.


Recruitment information / eligibility

Status Completed
Enrollment 268
Est. completion date February 19, 2019
Est. primary completion date February 19, 2019
Accepts healthy volunteers
Gender All
Age group 20 Years and older
Eligibility Inclusion Criteria:

- ASA I-II

- scheduled surgery who need general anesthesia

Exclusion Criteria:

- allergy to the BIS patch

- not suitable for general anesthesia

Study Design


Related Conditions & MeSH terms


Locations

Country Name City State
Taiwan National Taiwan University Hospital Taipei

Sponsors (1)

Lead Sponsor Collaborator
National Taiwan University Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type Measure Description Time frame Safety issue
Primary The gamma, beta, alpha and theta power of EEG We will try to observe the differences between hypnotic medications through EEG decomposed and power analysis. the total duration inclusions in operation room
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