The Electroencephalogram Analysis in the Differences Between Inhalation Anesthetic and Propofol.

Propofol Clinical Trial

Official title:

The Electroencephalogram Analysis in the Differences Between Inhalation Anesthetic and Propofol.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04431557
• Other study ID #: 201509018RINB
• Status: Completed
• Start date: July 19, 2017
• Est. completion date: February 19, 2019

Study information

• Verified date: July 2017
• Source: National Taiwan University Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The investigators will record 120 patients who received general anesthesia, their EEG data recorded from Bispectral Index (BIS) machine for emperical mode decomposition (EMD) analysis, the investigators decomposed EEG signal to different oscillations and tried to observe the differences between hypnotic medications through EEG analysis.

Description:

The electroencephalography (EEG) is a noninvasive medical technique for monitoring and recording the electrical activity of brain. The Hilbert-Huang transform (HHT) was proposed to decompose EEG signal into intrinsic mode functions (IMF) which can obtain instantaneous frequency data and work well for data that is nonstationary and nonlinear.

The relationship between frontal EEG patterns and hypnotics remain poorly understood. The investigators only can tell the increase in frontal EEG power and shift power to lower frequencies during general anesthesia from publications. The investigators are going to decompose EEG with HHT and find the energy shift during general anesthesia, compare with different anesthetics.

The investigators will record 120 patients who received general anesthesia, their EEG data recorded from BIS machine for EMD analysis, the investigators decomposed EEG signal to different oscillations and tried to observe the differences between hypnotic medications through EEG analysis.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 268
• Est. completion date: February 19, 2019
• Est. primary completion date: February 19, 2019
• Gender: All
• Age group: 20 Years and older

Eligibility

Inclusion Criteria:

• ASA I-II

• scheduled surgery who need general anesthesia

Exclusion Criteria:

• allergy to the BIS patch

• not suitable for general anesthesia

Related Conditions & MeSH terms

• Propofol
• Respiratory Aspiration
• Sevoflurane

Locations

Country	Name	City	State
Taiwan	National Taiwan University Hospital	Taipei

Sponsors (1)

Lead Sponsor	Collaborator
National Taiwan University Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The gamma, beta, alpha and theta power of EEG	We will try to observe the differences between hypnotic medications through EEG decomposed and power analysis.	the total duration inclusions in operation room