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Prophylaxis clinical trials

View clinical trials related to Prophylaxis.

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NCT ID: NCT04652648 Completed - Covid19 Clinical Trials

Rapid Development and Implementation of a Remote ECG-monitored Prospective Randomized Clinical Trial During a Pandemic: Hydroxychloroquine Prophylaxis in COVID-19 Household Contacts

Start date: May 27, 2020
Phase: Phase 4
Study type: Interventional

- organizing an entirely no in-person contact clinical trial is feasible during a 22 COVID-19 pandemic 23 - Remote smartphone 6-lead ECG monitoring is possible even in a group unfamiliar 24 with the technology 25 - Hydroxychloroquine used prophylactically at 200 mg BID had no observable 26 cardiotoxicity 27 - Additional study using this technique is warranted to look at reliability and cost-28 effectiveness

NCT ID: NCT04573270 Completed - Covid19 Clinical Trials

Mesenchymal Stem Cells for the Treatment of COVID-19

Start date: April 24, 2020
Phase: Phase 1
Study type: Interventional

This double blind, placebo controlled, multi-arm, multi-site study investigates the safety and efficacy of stem cell therapy for the treatment of patients admitted to hospital suffering complications from COVID-19 and the treatment of healthy subjects (healthcare providers) for prophylactic effect following those patients.

NCT ID: NCT04479579 Completed - Surgery Clinical Trials

Improved Adherence With Extended Venous Thromboembolism Prophylaxis After Major Cancer Surgery

Start date: February 22, 2021
Phase: Phase 4
Study type: Interventional

This is a prospective, twin-center, cohort study in patients discharged from the hospital after major abdominal or pelvic cancer surgery for cancer. This study is designed to evaluate the adherence to extended deep vein thrombosis prophylaxis (DVT) with the direct oral anticoagulant apixaban on the background of historical data from the investigator's center on low-molecular-weight heparin (LMWH) substandard adherence in the same setting.

NCT ID: NCT04031781 Completed - Episodic Migraine Clinical Trials

The Role of Left Prefrontal Transcranial Magnetic Stimulation in Episodic Migraine Prophylaxis

Start date: May 1, 2013
Phase: N/A
Study type: Interventional

The aim of the study was to examine the prophylactic role of repetitive transcranial magnetic stimulation (rTMS) on the frequency, and severity of migraine attacks in episodic migraineurs who failed medical treatment. A group received 5 rTMS sessions, delivered over one week. Each rTMS session consisted of a single train of 900 total pulses over 3 minutes duration given at 5-Hz frequency and 100% motor threshold intensity and the placebo group received rTMS with the same stimulation frequency at a fixed intensity of 50% of the machine output

NCT ID: NCT03675048 Completed - Dysbiosis Clinical Trials

Lactobacillus Reuteri DSM 17938 in Gut Microbiota Development in Infant Born by Caesarean Section

Start date: October 1, 2018
Phase: N/A
Study type: Interventional

The aim of this study is to assess influence of probiotic Lactobacillus reuteri DSM 17938 on formation of gut microbiota in infant born by Caesarean section. It is anticipated that daily using of probiotic Lactobacillus reuteri DSM 17938 can prevent development of early dysbiosis of gut microbiota induced by Caesarean section.

NCT ID: NCT03472040 Completed - Clinical trials for Hereditary Angioedema

A Long Term Safety Study of BCX7353 in Hereditary Angioedema

APeX-S
Start date: February 16, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

This is an open-label study to evaluate the long term safety and effectiveness of oral treatment with BCX7353 in preventing acute angioedema attacks in patients with Type I and Type II Hereditary Angioedema (HAE).

NCT ID: NCT02951702 Completed - Clinical trials for Clostridium Difficile Infection

Oral Vancomyin for Primary Clostridium Difficile Infection Prophylaxis in Patients Receiving High-Risk Antibiotics

Start date: November 2016
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine if oral vancomycin used as primary Clostridium difficile prophylaxis can reduce the incidence of this infection in high-risk patients.

NCT ID: NCT02362581 Completed - Hemophilia A Clinical Trials

Comparison of Prophylaxis and On-demand Treatment in Children With Moderate to Severe Hemophilia A

Start date: December 2012
Phase: N/A
Study type: Interventional

Comparison of prophylaxis and on-demand treatment in children with moderate to severe hemophilia A. This study determines to compare the efficacy of prophylaxis and on-demand treatment in moderate to severe hemophilia A children in King Chulalongkorn Memorial Hospital, Bangkok, Thailand

NCT ID: NCT01295606 Completed - Prophylaxis Clinical Trials

Cefazolin Pharmacokinetics: Elimination Clearance in Neonates

Start date: February 2011
Phase: Phase 4
Study type: Interventional

To document cefazolin disposition (concentration/time profile, protein binding, metabolism, renal elimination characteristics) and its covariates in neonates following intravenous administration of the drug at induction of anesthesia, prior to an invasive procedure To evaluate if optimalisation of cefazolin dose regimen during neonatal life is needed

NCT ID: NCT00853463 Completed - Pulmonary Embolism Clinical Trials

Discharge ALERT: Quality Improvement Initiative

Discharge
Start date: April 2009
Phase: N/A
Study type: Interventional

Brigham and Women's Hospital will coordinate a Quality Improvement Initiative at other hospitals that focuses on whether physician notification prior to discharge of high risk VTE patients will reduce the incidence of VTE after hospital discharge.