View clinical trials related to Prolonged Mechanical Ventilation.
Filter by:Background: The exercise intervention can help participants with prolonged mechanical ventilation improve ventilator weaning; however, the content of exercise intervention is diverse and inconsistent. Objective: This study aims to design the continuous mobility training and examine the clinical effects in participants with prolonged mechanical ventilation. Methods: This prospective, single-center, concealed allocation, evaluator-blind, randomized control study divided participants transferred from the intensive care unit to the respiratory care center into two groups. The control group underwent the routine ventilator weaning plan and hand bicycle training, while the experimental group underwent routine ventilator weaning plan and continuous mobility training plan. The success rate of ventilator weaning, length of mechanical ventilation, length of stay at the respiratory care center, and total length of hospital stay were analyzed.
Mechanical ventilation is an effective treatment for respiratory failure, no more than ten percent of patients with respiratory failure need long-term mechanical ventilation.
Prolonged mechanical ventilation has been defined as the need for >21 days. The muscle weakness occurred most commonly in patients with PMV and resulted in increasing time to wean from mechanical ventilation, and longer stay in hospital. Neuromuscular electrical stimulation (NMES) involves applying a stimuli to skeletal muscle, to trigger muscle contraction, and it can be used for the recovery of muscle mass and muscle strength following prolonged immobilization. NMES also improve microcirculation and systemic circulation in patients with cardiopulmonary diseases. The purposes of this study: 1. to examine the acute effects of NMES on the microcirculation, physiologic response and metabolic demand in patients with PMV. 2. to investigate the training effects of NMES on microcirculation, muscle strength and weaning outcomes in patients with PMV. METHODS: Subjects with PMV are recruited and are randomly assigned into NMES (n=20) or control group (n=20).The NMES group receive daily NMES for 30 min/session for 10 days. The assessment of muscle strength and weaning profile were performed before and after intervention. During the first and the last NMES session, the status of microcirculation and local muscle tissue oxygenation will be measured by NIRS, and the metabolic status will be measured by IC. The ventilator weaning rate and length of stay in RCC will be recorded.
The purpose of the study is to establish clinical determinants of poor cognitive and physical functional outcome of CCI patients so that the investigators may develop and validate a multi-dimensional clinical prediction model to more effectively inform decision making earlier in the course of the ICU care. The investigators hypothesize that multiple premorbid and acute factors measured early in the course of CCI will have strong independent associations with functional recovery. The investigators further hypothesize that social and economic factors are associated with long-term functional outcomes independent of the acute clinical problems.
This study aims to describe the patient characteristics, feasibility, and outcomes of an home mechanical ventilation (HMV) program at a university hospital in Thailand.
Deciding about prolonged life support for critically ill patients can be very difficult. Therefore, the investigators are doing a study to see if an internet-based decision aid can improve the quality of decision making for substitute decision makers of patients who are in the intensive care unit (ICU).
The purpose of this study is to test a communication intervention to support family decision-making for patients with chronic critical illness.