Prolapse Clinical Trial
Official title:
Pre- and Postoperative Dynamic Floor MRI in Order to Evaluate the Anatomical and Functional Changes of the Different Pelvic Floor Organs, Before and After Prolapse Surgery.
Pelvic organ prolapsed, associated with defecation disorders and urinary tracts symptoms are common and affect up to 25% of the population, mostly parous women. The pelvic floor must be seen as one entity, with multiple anatomical and physiological interactions between the various compartments (rectum, vagina, uterus and bladder) which are embedded in the same anatomical region. The often complex pathologies of this region should therefore be treated in a multidisciplinary setting. Besides clinical evaluation, functional dynamic imaging of anorectal and pelvic floor disfunctions has an important role in the diagnosis and management of these disorders. Although the colpocystodefecography is still considered to be the golden standard in imaging this complex anatomical region, there is clearly a need for more precise imaging of the structural details, preferentially without any irradiation. Transperineal ultrasound is an option but the investigators have chosen to evaluate the use of dynamic magnetic resonance imaging. In contrast to colpocystodefecography, dynamic pelvic floor magnetic resonance imaging is an evolving technology and its precise role in functional imaging of the pelvic floor still remains to be determined. Prolapse surgery is commonly performed and therefore it is important to assess the efficacy of the operations in correcting the anatomical defects and the symptoms associated without creating new, pelvic floor related symptoms. Few studies exist today allowing the assessment of the anatomical changes and symptoms after surgery, through abdominal or perineal approach. This study will evaluate the reliability of the dynamic pelvic floor imaging, done in a sitting position, compared to colpocystodefecography, done in a sitting position. It will also compare clinical objective and subjective results related to pelvic floor abnormalities with imaging. Finally, it will evaluate the anatomical changes in correlation with the clinical results, organ position and inter-compartments relationships after surgery. This study will allow to understand and explain some relapses and failures and could lead to an improvement of the indications for surgery and surgical techniques used.
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03609229 -
Outcomes After Sacrocolpopexy With and Without Burch to Prevent Stress Urinary Incontinence in 3rd and 4th Degree Apical Uterine Prolapse
|
N/A | |
Completed |
NCT04523298 -
Use of Non-ablative Vaginal Erbium YAG Laser for the Treatment of Prolapse
|
N/A | |
Completed |
NCT04275089 -
Early Feasibility Study of the Reia Vaginal Pessary
|
N/A | |
Recruiting |
NCT01608568 -
Affixing Polypropylene Mesh Using Barbed Suture (Quillâ„¢ SRS) During Robotic Assisted Laparoscopic Sacrocolpopexy
|
N/A | |
Completed |
NCT01551992 -
Affixing Polypropylene Mesh Using Barbed Suture (Quillâ„¢ Srs) During Laparoscopic Sacrocolpopexy Randomized Controlled Trial (Quill Lsc)
|
N/A | |
Completed |
NCT03307824 -
Operative Time During the Use of the Synthetic Glue IFABONDTM in Laparoscopic Sacrocolpopexy
|
N/A | |
Recruiting |
NCT04010292 -
Enhancing Patient Recall in Urogynecologic Surgery
|
N/A | |
Terminated |
NCT00099372 -
Long-term Effectiveness of Abdominal Sacrocolpopexy for the Treatment of Pelvic Organ Prolapse
|
||
Recruiting |
NCT05964881 -
PDS Versus Prolene as Suture Material for Vaginal Sacrospinous Hysteropexy
|
N/A | |
Completed |
NCT03890471 -
Telephone Intervention to Increase Patient Preparedness and Satisfaction Trial (TIPPS): A Randomized Control Trial
|
N/A | |
Recruiting |
NCT04440475 -
Tap Block vs Conventional Pain Medication for Patients Undergoing Robotic Sacrocolpopexy
|
N/A | |
Active, not recruiting |
NCT04410393 -
Sacrocolpopexy and Lateral Suspension Operations
|
||
Completed |
NCT03624764 -
Assisted Promontofixation Using Glue Versus Promontofixation Using Threads (PROCOL)
|
N/A | |
Completed |
NCT03820089 -
Evaluation of TP US in Women With Prolapse
|
||
Completed |
NCT01779544 -
Rehabilitation After Lumbar Disc Surgery: Exercise Therapy and Brief Educational Intervention
|
N/A | |
Completed |
NCT00271102 -
Surgical Study Comparing 2 Procedures for the Treatment of a Dropped Bladder
|
N/A | |
Completed |
NCT05474495 -
Transversus Abdominis and Pelvic Floor Muscle Strengthening Exercise Program In Patients With Grade 1 Cystocele
|
N/A | |
Withdrawn |
NCT00827645 -
Uterine Artery Embolization and Pelvic Floor Symptoms
|
||
Completed |
NCT01805310 -
Pre-operative Bowel Preparation Prior to Minimally Invasive Sacral Colpopexy
|
Phase 4 | |
Completed |
NCT04099121 -
Evaluation of 3D Translabial Ultrasound Imaging for Pessary Size Estimation
|
N/A |