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Prolapse clinical trials

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NCT ID: NCT06176521 Recruiting - Clinical trials for Pelvic Organ Prolapse

Evaluation of the Results of Laparoscopic Sacrohysteropexy and Sacrocolpopexy Surgeries Performed Without Mesh in the Surgical Treatment of Pelvic Organ Prolapse

Start date: November 1, 2023
Phase: N/A
Study type: Interventional

Evaluation of the anatomical and functional results of laparoscopic sacrohysteropexy and sacrocolpopexy surgeries performed without using mesh in the surgical treatment of pelvic organ prolapse

NCT ID: NCT06174584 Completed - Rectal Prolapse Clinical Trials

Comparison of Cow Milk and 15% Hypertonic Saline in the Treatment of Rectal Prolapse in Children

Start date: February 1, 2021
Phase: Early Phase 1
Study type: Interventional

To see the outcome of results of Cow Milk & Hypertonic Saline in the treatment of Rectal Prolapse in Children

NCT ID: NCT06159777 Not yet recruiting - Constipation Clinical Trials

Pre-operative Polyethylene Glycol 3350 for Minimally Invasive Urogynecologic Surgery

Start date: August 2024
Phase: Phase 4
Study type: Interventional

The goal of this clinical trial is to test the use of a laxative before surgery in women having surgery to fix pelvic prolapse that do not have constipation. The main question it aims to answer is: Does use of a laxative before surgery lessen the discomfort of bowel movements after surgery? Participants will be asked to complete questionnaires before and after surgery. Researchers will compare using the laxative before and after surgery versus only after surgery to see if there is less discomfort with bowel movements after surgery.

NCT ID: NCT06128291 Active, not recruiting - Prolapse; Female Clinical Trials

Concomitant Posterior Colporrhaphy on Bowel Functions in Pelvic Organ Prolapse Repair

Start date: March 3, 2023
Phase:
Study type: Observational

Compare the changes of preoperative and postoperative posterior colporrhaphy.

NCT ID: NCT06126328 Completed - Clinical trials for Pelvic Organ Prolapse

Materna Prep Study Phase II

EASE
Start date: September 8, 2021
Phase: Phase 2
Study type: Interventional

This study is designed to evaluate the safety and effectiveness of the Materna Prep Device in reducing pelvic muscle injuries during vaginal delivery. Subjects are randomized to Materna Prep Device or Standard of Care without use of the Materna Prep Device Intervention with the Materna Prep Device is expected to be a one-time use of approximately 30-90 minutes during the 1st stage of labor. Subject participation in the study is targeted to be 3 months from the time of the use of the device during delivery with optional long-term follow-up.

NCT ID: NCT06120530 Recruiting - Clinical trials for Pelvic Organ Prolapse

Intraperitoneal Bupivacaine for Pelvic Organ Prolapse

Start date: August 15, 2023
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the effects of 30 mL intraperitoneal Bupivacaine without epinephrine 0.25% on postoperative pain control in patients undergoing pelvic organ prolapse repair. The investigators hypothesize that use of intraperitoneal Bupivacaine will decrease postoperative pain scores and opiate consumption in the postoperative period, following pelvic organ prolapse repair.

NCT ID: NCT06117670 Recruiting - Clinical trials for Pelvic Organ Prolapse

Gamma-irradiated Amniotic Membrane Graft in Posterior Colporrhaphy

Start date: November 1, 2023
Phase: Phase 3
Study type: Interventional

The goal of this clinical trial is to test the benefit of using gamma-irradiated amniotic membrane as a graft in surgical repair for women with posterior vaginal wall defects. The main question it aims to answer is: • Is posterior colporrhaphy using gamma-irradiated amniotic membrane as a graft effective? Participants will undergo posterior colporrhaphy, which will be modified by adding gamma-irradiated amniotic membrane as a graft during the repair.

NCT ID: NCT06079892 Recruiting - Hemorrhoid Prolapse Clinical Trials

Hemorrhoid Radiofrequency

RFH
Start date: March 1, 2017
Phase:
Study type: Observational

Triapedicular haemorroidectomy is currently the gold standard in haemorrhoidal pathology. Minimally invasive surgical techniques now play an important role in the haemorrhoidal management algorithm, particularly for less advanced stages of the disease. Among these techniques, radiofrequency is one of the most recent and is gradually gaining ground. It involves applying a radiofrequency current to the internal haemorrhoidal tissue in order to induce its involution. The literature has shown that this technique leads to symptomatic improvement in over 60% of cases and a high satisfaction rate, even though some patients still seem to have haemorrhoidal symptoms postoperatively. The aim of this study is to evaluate the efficacy of this technique in patients with haemorrhoidal pathology operated on at our centre, using "hard" criteria which are thought to be more rigorous ("cure" rather than "improvement").

NCT ID: NCT06072456 Completed - Clinical trials for Pelvic Organ Prolapse

Comparison of Vaginal Axis on MRI in Alternative Apical Prolapse Surgeries to Sacrocolpopexy

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

Sacrocolpopexy remains the preeminent modality in addressing apical prolapse surgically. Nevertheless, amplified morbidity rates within cohorts characterized by obesity and advanced age constrain the advantages conferred by the procedure. Recent years have witnessed a proliferation of inquiries appraising the efficacy of laparoscopic lateral suspension, pectopexy, and sacrospinous ligament fixation interventions, which have, over time, garnered extensive clinical application, in relation to recurrence rates. A multitude of investigations have been undertaken to delineate the optimal vaginal axis. In the present investigation, we have delineated a research protocol aimed at scrutinizing these alternative surgical modalities with regard to their impact on the vaginal axis.

NCT ID: NCT06051916 Recruiting - Clinical trials for Surgery-Complications

Post-operative Residual Voiding Volume Following Bulking and Vaginal Prolapse Surgery and Impact on In-hospital Stay

POUR
Start date: November 1, 2023
Phase: N/A
Study type: Interventional

Post operative urinary retention is a commonly observed complication following women undergoing urogynecology surgery. The trial includes patients undergoing bulking and vaginal prolapse surgery, who are randomized in two postoperative groups prior to surgery in order to test two void regimes. One group includes a strict voiding regime, where patients are discharged when voiding volume is minimum 150 ml and residual volume is maximum 200 ml. Comparatively, the minimalistic voiding group discharge patients after one spontaneous voiding, independent of voiding volume and residual volume. The primary aim of this study is to evaluate time to discharge in two different voiding trials techniques (strict vs minimalistic) after anterior, posterior or vaginal vault prolapse surgery as well as bulking surgery. Secondly, to register the development of postoperative urinary tract infection, urine retention, gynecological pain and patients' calls to the gynecological ward after discharge.