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Prolapse clinical trials

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NCT ID: NCT00965952 Completed - Clinical trials for Pelvic Organ Prolapse

A Surgical Simulation Study to Evaluate the Safety of a Device Mechanism as Treatment for Vaginal Apical Prolapse

Start date: July 2009
Phase: N/A
Study type: Observational

The purpose of this pilot study is to perform a procedure to evaluate the safety of the placement of a new device (known as the VFIX device).

NCT ID: NCT00964197 Completed - Clinical trials for Pelvic Organ Prolapse

The Purpose of This Study is to Look at Pelvic Support Problems, Also Commonly Known as Pelvic Organ Prolapse

Start date: November 2008
Phase: N/A
Study type: Interventional

FemmeJock is a pelvic floor support system developed by pelvic floor physiotherapists for patients with pelvic organ prolapse in order to ameliorate symptoms of pelvic floor pressure and discomfort. The device is a girdle to be worn on the outside of underwear. The device is machine washable and there are no documented risks with wearing it. This product is currently being used by pelvic floor physiotherapists and has been subjectively reported by individual accounts as being successful in improving pelvic floor symptoms. The efficacy of this product has not been previously studied in women with pelvic organ prolapse. The investigators are proposing a pilot study with the following specific aims: 1. to assess patient satisfaction and continuation of use of the FemmeJock support system after 3 months of treatment. 2. to describe, if any, the reasons for discontinuation associated with the use of this product, and 3. to assess whether women experience improvement of pelvic floor symptoms after using this product.

NCT ID: NCT00955448 Completed - Clinical trials for Anterior Pelvic Organ Prolapse

Trial of Small Intestine Submucosa (SIS) Mesh for Anterior Repair: A Pilot Study

Anterior SIS
Start date: December 2009
Phase: Phase 3
Study type: Interventional

Prolapse occurs when pelvic organs drop down and cause a bulging of the tissues. An "anterior wall prolapse" occurs when the front of the vagina loses its support, and the bladder drops down and rotates into the vaginal opening. The bladder can cause a bulge out of the vagina. One of the treatment options available is to repair the anterior wall surgically. The goals of surgery are to return the anatomy to its usual position, ensuring that all the pelvic floor organs (bladder, vagina and rectum) can function properly. The ideal surgical repair would also be long lasting. Two surgical options are routinely performed in Calgary for repair of an anterior compartment prolapse. One option involves fixing the organs back in place using sutures. The other option uses sutures plus a mesh made of small intestine submucosa (SIS) that is already licensed for use in Canada. The SIS mesh is slowly absorbed after it is placed in the pelvic area. The investigators do not know which of these two options is the best surgical procedure. Both may have different advantages that would result in better results. This study is designed to try and find out if one of these procedures is better, and if a larger study may be needed.

NCT ID: NCT00952406 Completed - Clinical trials for Pelvic Organ Prolapse

A Multi Center Study to Validate a Condition-specific Measure of Sexual Health in Women With Pelvic Floor Disorders

Start date: August 2009
Phase: N/A
Study type: Observational

Study Aims: 1. To validate a new measure of sexual function and activity in women with PFDs; 2. To establish the responsiveness to change of the new measure. The investigators hypothesis is that the investigators can create a new questionnaire that accurately measures sexual health in women with pelvic floor disorders that improves on the already published questionnaires.

NCT ID: NCT00946205 Completed - Rectal Prolapse Clinical Trials

Laparoscopic Rectopexy for Rectal Prolapse

Start date: September 2006
Phase: N/A
Study type: Interventional

The aim of the present prospective, double-blind, randomized study is to study whether laparoscopic anterior mesh rectopexy is as good as laparoscopic posterior rectopexy with respect to obstructive defecation afterwards.

NCT ID: NCT00937430 Completed - Clinical trials for Pelvic Organ Prolapse

Bowel Preparation and Pelvic Organ Prolapse Surgery

Start date: March 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to find out if performing a bowel preparation prior to pelvic organ prolapse surgery has any effect on the return of bowel function after surgery.

NCT ID: NCT00860912 Completed - Clinical trials for Pelvic Organ Prolapse

Veritas Collagen Matrix Cystocele Repair Study - Postmarketing

Start date: December 2001
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the Veritas Collagen Matrix in treating female patients with documented occurence of Pelvic Organ Prolapse as evidenced by a cystocele.

NCT ID: NCT00859417 Completed - Anterior Prolapse Clinical Trials

Study Evaluating the Effectiveness of the Use of Prosthesis With Trans-Obturator Way for the Correction of Anterior Prolapse

Start date: September 2008
Phase: N/A
Study type: Interventional

The classical surgical treatment of an anterior prolapse is the use of autologous tissue. In front of the high rate of recurrences with this technique, the use of synthetic prosthesis made their appearance. But the drawback of the use of prosthesis is their tolerability. The system Perigee®, a prosthetic kit by trans-obturator way, was designed to obtain high efficiency in the correction of the prolapse while reducing the risk of complications. The lack of prospective and randomized studies makes difficult to assess the interest. The investigators, therefore, have put in place a randomized prospective study seeking the evaluation of the system Perigee® compared to the conventional surgical technique.

NCT ID: NCT00833001 Completed - Cystocele Clinical Trials

Clinical Performance of the GYNECARE PROLIFT + M* Pelvic Floor Repair System as a Device for Pelvic Organ Prolapse

Start date: April 2008
Phase: Phase 2/Phase 3
Study type: Observational

The purpose of this study is to evaluate the clinical performance of the PROLIFT system with a new lighter-weight mesh in repair of vaginal prolapse.

NCT ID: NCT00827528 Completed - Clinical trials for Pelvic Organ Prolapse

SIS Graft and Traditional Repair in Vaginal Wall Prolapse

Start date: August 2006
Phase: Phase 4
Study type: Interventional

The objective of this study is to evaluate surgical treatment of anterior vaginal wall prolapse using the sis graft or traditional repair. This a randomized and prospective study. Clinical patterns that will be evaluated: anatomic results of surgery; impact of surgery in quality of life using the Pelvic Organ Prolapse Questionnaire (P-QoL), sexual function with FSFI and possible complications.