Clinical Trials Logo

Prolapse clinical trials

View clinical trials related to Prolapse.

Filter by:

NCT ID: NCT01945580 Completed - Clinical trials for Pelvic Organ Prolapse

Xenform Postmarket Surveillance Study

Xenform
Start date: February 10, 2014
Phase: N/A
Study type: Interventional

To compare transvaginal repair with a biologic graft to traditional native tissue repair in women surgically treated for anterior and/or apical pelvic organ prolapse.

NCT ID: NCT01917968 Completed - Clinical trials for Pelvic Organ Prolapse

Uphold LITE Post-Market Surveillance Study

Uphold LITE
Start date: October 10, 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to compare transvaginal mesh repair to traditional native tissue repair in women surgically treated for anterior and/or apical pelvic organ prolapse.

NCT ID: NCT01864408 Completed - Clinical trials for Pelvic Organ Prolapse

Interactive Web-Based Tool for Pelvic Organ Prolapse: Impact on Patient Understanding and Provider Counseling

iPad
Start date: May 2012
Phase: N/A
Study type: Interventional

The primary aim is to assess whether an interactive patient/provider counseling process using a web-based tool (iPadTM) will improve patient satisfaction regarding understanding of her bulge symptoms. The secondary aims are to assess whether an interactive patient/provider counseling process using web-based tool (iPadTM) will: 1. Decrease patient anxiety with counseling 2. Improve patient satisfaction with counseling 3. Improve provider knowledge, anxiety, and satisfaction with counseling 4. Be easy to use in clinic 5. Be actually used in clinic

NCT ID: NCT01852422 Completed - Clinical trials for Pelvic Organ Prolapse

Location and Anatomic Characterization of the Sacrospinous Ligaments in Women With Pelvic Organ Prolapse

Start date: June 2013
Phase:
Study type: Observational

Pelvic organ prolapse is a common disorder that results in significant patient morbidity. Approximately 1 in 9 women undergo surgery for the correction of pelvic organ prolapse (POP) and associated bladder and bowel dysfunction. Despite its common occurrence, the cause of POP remains largely unknown. Prolapse is thought to be caused by direct injury to the levator ani (LA) muscle, denervation of the pelvic floor musculature, or fascial damage incurred during childbirth trauma. The sacrospinous ligaments are commonly employed surgical structures employed to repair vaginal prolapse. Despite the frequent use of these structures in prolapse surgery, there is a paucity of information regarding the identification of these structures outside of surgical dissection. Furthermore, there is no published data describing the relative distances between the apex of the vagina and these ligaments in women with prolapse. Recent developments in imaging have enabled the identification of the distal subdivisions of the levator ani, classifying as: pubovaginalis, puboanalis, and the puboperinealis as the subdivisions of the pubovisceralis. The visualization of these structures is possible using a 3D ultrasound technique (BK medical, Wilmington, MA), that has been validated in cadavers and in live humans, with excellent interrater reliability. The investigators propose to use this technology to explore the anatomy of the sacrospinous ligaments.

NCT ID: NCT01842464 Completed - Clinical trials for Pelvic Organ Prolapse

Sacro-Spinous Ligaments Anterior Apical Anchoring

Start date: September 2011
Phase: N/A
Study type: Observational

Anterior-apical compartment mesh implants for pelvic floor reconstruction are anchored here to the Sacro-Spinous ligaments and evaluated being a feasible and effective method.

NCT ID: NCT01840176 Completed - Clinical trials for Vaginal Vault Prolapse

Prophylactic Modified McCall Culdoplasty During Total Laparoscopic Hysterectomy

Start date: May 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the feasibility of performing prophylactic McCall culdoplasty at the time of total laparoscopic hysterectomy. The investigators will also be measuring pelvic support (using POP-Q) and sexual function before and at different time points (up to 12 months) postoperatively. The investigators hypothesize that women undergoing the McCall culdoplasty will not have different immediate surgical outcomes (operative time, etc) and may have better pelvic support and sexual function in the future.

NCT ID: NCT01827774 Completed - Clinical trials for Pelvic Organ Prolapse

Soft Tissue Graft for Repair of Pelvic Organ Prolapse

POP
Start date: March 2013
Phase: N/A
Study type: Interventional

The purpose of this Study is to collect information about the performance of the Surgisis® Soft Tissue Graft ("Study Product") for the repair of pelvic organ prolapse in women.

NCT ID: NCT01823055 Completed - Clinical trials for Surgical Repair of Middle Compartment Prolapse (Vaginal Vault or Uterine Prolapse) With or Without Cystocele

Safety and Efficacy of a Transvaginal Suture Capturing Mesh Device

Start date: January 2012
Phase: N/A
Study type: Interventional

To perform a clinical safety and efficacy assessment of the Uphold LITE system for pelvic organ prolapse in a prospective multicenter, single cohort study.

NCT ID: NCT01805310 Completed - Clinical trials for Pelvic Organ Prolapse

Pre-operative Bowel Preparation Prior to Minimally Invasive Sacral Colpopexy

Start date: February 2013
Phase: Phase 4
Study type: Interventional

Prior to surgery, gynecologists and urogynecologists have routinely prescribed preoperative mechanical bowel preparations in attempts to decrease the risk of infection, while also providing easier bowel manipulation and better visualization during surgery. However, many of these proposed benefits have never been proven, and usage of bowel preparations amongst surgeons remains highly variable. In both the general surgery and gynecology literature, researchers have begun to question the need for the vigorous preparations. Aside from surgical visualization, urogynecologists have additional concerns about how bowel preparations may impact postoperative bowel function given up to half of women with pelvic floor disorders have baseline constipation and straining is known to impact surgical recovery. Many studies have addressed various postoperative fiber and laxative preparations in attempts to improve postoperative bowel-related symptomatology, but none have specifically looked at preoperative bowel preparations. This study aims to determine if mechanical bowel preparation prior to minimally invasive sacral colpopexy affects patients' postoperative recovery, specifically related to bowel symptomatology; operative or post-operative complications; surgeons' perceptions of surgical difficulty directly attributed to the bowel; and post-operative return of normal bowel function.

NCT ID: NCT01779544 Completed - Prolapse Clinical Trials

Rehabilitation After Lumbar Disc Surgery: Exercise Therapy and Brief Educational Intervention

Start date: January 2013
Phase: N/A
Study type: Interventional

Rehabilitation after lumbar disc surgery (prolapse) focuses on various elements such as endurance, strength, stretching and information. Evidence concludes that it is not harmful to return to activity after lumbar disc surgery, and restrictions to activities after these operations are today more or less nonexistent. Some studies have shown that high intensity programs might be more effective, but they are probably more expensive. In recent years cognitive interventions have received more attention in rehabilitation programs after lumbar disc surgery. The cognitive approach is focused on providing patient knowledge to reduce uncertainty so that he or she can understand what is important after lumbar disc surgery so that belief in self-efficacy increases. A goal of the rehabilitation is to get the patient to resume normal activities. Reviews ask for how much treatment are needed in a rehabilitation program after lumbar disc surgery. The study will be a randomized clinical trial. The study will compare two different post-operative rehabilitation programs (general information or general information + exercise therapy). Both groups will begin treatment 1 day after surgery. Subjects in exercise therapy group are supposed to continue with exercises 3 months. In this study the following hypothesis will be studied: 1. Brief intervention, an educational model, alone after lumbar disc surgery do have the same effect on pain in legs and low back as brief intervention, an educational model, combined with exercise therapy. 2. Exercises which are instructed after lumbar disc surgery in a rehabilitation program, are being done by the patients.