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Prolapse clinical trials

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NCT ID: NCT06260436 Recruiting - Clinical trials for Pelvic Organ Prolapse

Questionnaire of Lower Urinary Tract Symptoms Among Women Before and After Surgical Correction of Uterine Prolapse

Start date: May 30, 2021
Phase:
Study type: Observational

. The study will include patients who underwent Pelvic reconstructive surgery for advanced pelvic organ prolapse (POP-Q ≥ 3). Data regarding preoperative evaluation, surgical procedure, and post-operative management will be collected. women will receive a follow up questionnaire. . The baseline questionnaire included data on age, urinary incontinence, daytime frequency, nocturia, postmicturition dribble, straining, urgency, incomplete bladder emptying, and hesitancy. Women were asked about leakage caused by coughing or sneezing, moving, lifting, sleeping, sexual intercourse, urgency, and rest.

NCT ID: NCT06255457 Recruiting - Clinical trials for Ventricular Tachycardia

Ventricular Arrhythmias in Patients Undergoing Mitral Valve Surgery

Mitra-VT
Start date: February 21, 2024
Phase:
Study type: Observational

Study objectives: - To assess the impact of mitral valve surgery for mitral regurgitation on ventricular arrhythmic burden and surrogate markers of fibrosis in patients with arrhytmogenic mitral valve prolapse (MVP) from baseline to 6 months after surgery - To characterize the molecular landscape of arrhytmogenic MVP Study design: -Prospective explorative observational study Study population: -90 patients with arrhytmogenic MVP and without arrhytmogenic MVP (controls) eligible for mitral valve surgery for mitral regurgitation will be enrolled. All patients will be evaluated with cardiac magnetic resonance (CMR) imaging and continuous seven day arrhythmic monitoring before and at 6 months after mitral valve surgery

NCT ID: NCT06253689 Recruiting - Clinical trials for Pelvic Organ Prolapse Vaginal Surgery

Impact of Defecation Posture on Ease of First Bowel Movement Following Posterior Repair

Start date: February 19, 2024
Phase: N/A
Study type: Interventional

This study will determine if defecation posture, when using a defecation posture modification device (DPMD), improves ease with first bowel movement following pelvic reconstructive surgery, specifically posterior repair.

NCT ID: NCT06246721 Recruiting - Clinical trials for Pelvic Organ Prolapse

Attitude and Success Rate of Women With Pelvic Organ Prolapse on Self-management of Vaginal Pessary

Start date: February 2, 2024
Phase: N/A
Study type: Interventional

This is a prospective cohort study aims at assessing patient's attitude towards self-management of vaginal pessary, and identifying factors that affect patient's level of acceptance towards self-management.

NCT ID: NCT06245577 Recruiting - Clinical trials for Pelvic Organ Prolapse

Biological Mesh Versus Synthetic Mesh in Interdisciplinary RRP With SCP

BioSynIRS
Start date: January 30, 2024
Phase: N/A
Study type: Interventional

The purpose of the pilot study is to demonstrate the safety and efficacy of a biological mesh compared to a standard synthetic mesh for the planned procedure in the above-mentioned clinical picture. Subsequently, a multicentre, randomized intervention study is planned to confirm the results and evaluate the long-term outcomes.

NCT ID: NCT06176521 Recruiting - Clinical trials for Pelvic Organ Prolapse

Evaluation of the Results of Laparoscopic Sacrohysteropexy and Sacrocolpopexy Surgeries Performed Without Mesh in the Surgical Treatment of Pelvic Organ Prolapse

Start date: November 1, 2023
Phase: N/A
Study type: Interventional

Evaluation of the anatomical and functional results of laparoscopic sacrohysteropexy and sacrocolpopexy surgeries performed without using mesh in the surgical treatment of pelvic organ prolapse

NCT ID: NCT06120530 Recruiting - Clinical trials for Pelvic Organ Prolapse

Intraperitoneal Bupivacaine for Pelvic Organ Prolapse

Start date: August 15, 2023
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the effects of 30 mL intraperitoneal Bupivacaine without epinephrine 0.25% on postoperative pain control in patients undergoing pelvic organ prolapse repair. The investigators hypothesize that use of intraperitoneal Bupivacaine will decrease postoperative pain scores and opiate consumption in the postoperative period, following pelvic organ prolapse repair.

NCT ID: NCT06117670 Recruiting - Clinical trials for Pelvic Organ Prolapse

Gamma-irradiated Amniotic Membrane Graft in Posterior Colporrhaphy

Start date: November 1, 2023
Phase: Phase 3
Study type: Interventional

The goal of this clinical trial is to test the benefit of using gamma-irradiated amniotic membrane as a graft in surgical repair for women with posterior vaginal wall defects. The main question it aims to answer is: • Is posterior colporrhaphy using gamma-irradiated amniotic membrane as a graft effective? Participants will undergo posterior colporrhaphy, which will be modified by adding gamma-irradiated amniotic membrane as a graft during the repair.

NCT ID: NCT06079892 Recruiting - Hemorrhoid Prolapse Clinical Trials

Hemorrhoid Radiofrequency

RFH
Start date: March 1, 2017
Phase:
Study type: Observational

Triapedicular haemorroidectomy is currently the gold standard in haemorrhoidal pathology. Minimally invasive surgical techniques now play an important role in the haemorrhoidal management algorithm, particularly for less advanced stages of the disease. Among these techniques, radiofrequency is one of the most recent and is gradually gaining ground. It involves applying a radiofrequency current to the internal haemorrhoidal tissue in order to induce its involution. The literature has shown that this technique leads to symptomatic improvement in over 60% of cases and a high satisfaction rate, even though some patients still seem to have haemorrhoidal symptoms postoperatively. The aim of this study is to evaluate the efficacy of this technique in patients with haemorrhoidal pathology operated on at our centre, using "hard" criteria which are thought to be more rigorous ("cure" rather than "improvement").

NCT ID: NCT06051916 Recruiting - Clinical trials for Surgery-Complications

Post-operative Residual Voiding Volume Following Bulking and Vaginal Prolapse Surgery and Impact on In-hospital Stay

POUR
Start date: November 1, 2023
Phase: N/A
Study type: Interventional

Post operative urinary retention is a commonly observed complication following women undergoing urogynecology surgery. The trial includes patients undergoing bulking and vaginal prolapse surgery, who are randomized in two postoperative groups prior to surgery in order to test two void regimes. One group includes a strict voiding regime, where patients are discharged when voiding volume is minimum 150 ml and residual volume is maximum 200 ml. Comparatively, the minimalistic voiding group discharge patients after one spontaneous voiding, independent of voiding volume and residual volume. The primary aim of this study is to evaluate time to discharge in two different voiding trials techniques (strict vs minimalistic) after anterior, posterior or vaginal vault prolapse surgery as well as bulking surgery. Secondly, to register the development of postoperative urinary tract infection, urine retention, gynecological pain and patients' calls to the gynecological ward after discharge.