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Prolapse clinical trials

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NCT ID: NCT06004089 Completed - Clinical trials for Pelvic Organ Prolapse

Vaginal Transluminal Endoscopic Sacrocolpopexy

Start date: October 1, 2021
Phase: N/A
Study type: Interventional

This study aims to evaluate the outcomes of V-NOTES sacrocolpopexy following vaginal hysterectomy, focusing on perioperative and early postoperative results. The impact of V-NOTES sacrocolpopexy on patients' quality of life is investigated using validated assessment tools. Additionally, operative time, complications, pain scores were assessed.

NCT ID: NCT06000215 Completed - Clinical trials for Ultrasound Therapy; Complications

Credibility of Ultrasound Detection of Female Genital Prolapse Mesh

KIDS
Start date: October 21, 2018
Phase:
Study type: Observational

The aim of the study is to investigate the credibility of ultrasound in detection of synthetic polypropylene vaginal implants. In detail, the study investigates if the ultrasound examiner experience and the standard method of examination may affect the detection of synthetic polypropylene vaginal implants by ultrasound. The primary hypothesis is if 90% of prolapse mesh could be detected by the ultrasound examiners who are blinded to the previous prolapse surgery, the ultrasound is credible for prolapse mesh detection. The secondary hypothesis is if the ultrasound detection is not significantly different between the ultrasound examiners, the method of ultrasound examination is mandatory to acheive credible ultrasound detection of the prolapse mesh.

NCT ID: NCT05915936 Completed - Rectal Prolapse Clinical Trials

LVMR Versus PSR for External FTRPin Elderly Patients

Start date: April 1, 2012
Phase:
Study type: Observational

In frail patients with external full-thickness rectal prolapse (FTRP), the exact postoperative recurrence and functional result outcomes difference between Laparoscopic ventral mesh rectopexy (LVMR) and perineal stapler resection (PSR) have not been investigated, leading to ineffective treatment. Objectives: Evaluating the efficacy of PSR versus LVMR for treating external FTRP in the elderly. Design: This was a retrospective study that involved multiple centers. Settings: This study was conducted in the colorectal surgical units of our Universities' Hospitals Patients: 330 elderly patients divided into LVMR group (250), and PSR (80) between April 2012 and April 2019. Before and after surgery, patients were evaluated using the Wexner Incontinence Scale, the Altomare Constipation Scale, and the patient's satisfaction. Main outcomes measurement: The primary outcome was the recurrence rate and risk factors of FTRP. Secondary outcomes were postoperative incontinence and constipation and patients' satisfaction.

NCT ID: NCT05836532 Completed - Clinical trials for Mitral Regurgitation

Long Term Results of Surgical and Percutaneous Double Orefices Mitral Repair in Patient With p2 Prolapse Causing Degenerative Mitral Regurgitation

Start date: October 5, 2019
Phase:
Study type: Observational

Mitral regurgitation is a pathology affecting the left atrioventricular valve that causes a volumetric and pressure overload in the left chambers due to the loss of unidirectionality normally guaranteed by the cardiac valve system. The gold standard for severe mitral regurgitation is currently mitral valve plastic surgery. Edge to edge, on the other hand, allows shorter CEC and aortic clamping times and does not require significant surgical experience in the field of mitral valve repair, therefore edge to edge could be an excellent strategy in patients suffering from mitral regurgitation caused by P2 prolapse when quadrangular resection cannot be performed. The main objective of the present study is to examine the medium to long-term outcomes (in terms of survival and plastic outcomes) of patients undergoing central edge-to-edge to treat posterior flap pathology (P2).

NCT ID: NCT05770973 Completed - Ptosis, Eyelid Clinical Trials

Effect of Eyelid Patching After Ptosis Surgery

Start date: July 1, 2020
Phase: N/A
Study type: Interventional

The goal of this randomized, controlled, observer-blinded study is to compare the effect of compression dressing after ptosis surgery. The main question it aims to answer are: Effect of dressing on edema, hematoma, scar formation, ocular surface irritation and postoperative pain. Patients are randomized after surgery for compression dressing or not. Results are scored by a blinded observer. type of study: clinical trial

NCT ID: NCT05741567 Completed - Clinical trials for Anterior Prolapse Surgery Using the Transobturator Repair by Vaginal Plastron

Transobturator Repair by Vaginal Plastron

CYSPTO
Start date: October 13, 2022
Phase:
Study type: Observational

The autologous vaginal route consists of repairing the genital prolapse through the vagina using the patient's tissues without a prosthesis. Vaginal prostheses are actually currently prohibited in France [1, 2]. The autologous vaginal route is the quickest surgery and it can be done under spinal anesthesia, which constitutes arguments for offering it to elderly and fragile patients. The autologous vaginal approach gives functional and subjective results similar to promontofixation [2]. There are many surgical techniques that make it difficult to assess the recurrence rate in the literature. Autologous vaginal surgery provides a good degree of satisfaction for patients despite the risk of recurrence [3]. We propose to describe the results of the transobturator cystocele repair by vaginal plastron, a technique which seems reproducible and effective to us.

NCT ID: NCT05719584 Completed - Clinical trials for Pelvic Organ Prolapse

Pelvic Floor Muscle Training With and Without Hypopressive Exercises in Postmenopausal Females.

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

To compare the effects of pelvic floor muscle training with and without hypopressive exercises on pelvic organ prolapse in postmenopausal females

NCT ID: NCT05707533 Completed - Clinical trials for Pelvic Organ Prolapse

Vaginal Adventitia Reserved and Anatomical Implant Technique of Transvaginal Mesh Procedure for Pelvic Organ Prolapse

Start date: August 1, 2022
Phase:
Study type: Observational

After obtaining an institutional ethics approval (#2021833), the investigators retrospectively reviewed patients with Pelvic organ prolapse (POP) who underwent Transvaginal Mesh (TVM) in their hospital during June 2008 and December 2020. The goal of this observational study is to introduce the Vaginal Adventitia Reserved and Anatomical Implant Technique in Transvaginal mesh surgery, and to report long term efficacy and safety results of this technique. The main questions it aims to answer are: - How to reduce the potential risk of mesh-related complications when performing TVM? - How effective is the use of the Vaginal Adventitia Reserved and Anatomical Implant Technique when performing TVM? Participants will be asked to fill the Pelvic Floor Distress Inventory (PFDI-20) at final follow-up, and the Prosthesis/Graft Complication Classification Code was used to record the mesh-related complications.

NCT ID: NCT05697796 Completed - Clinical trials for Pelvic Organ Prolapse

Comparison of Post-operative Symptoms After Two Surgeries for Patients With Pelvic Organ Prolapse

Start date: November 1, 2022
Phase:
Study type: Observational

Collect and review the patients who underwent surgical treatment due to pelvic floor organ prolapse from 2020 to 2021, make statistics on their postoperative questionnaire data, and evaluate the clinical effects of different surgical methods

NCT ID: NCT05571072 Completed - Opioid Use Clinical Trials

Opioid Use After Urogynecologic Procedures: Using a Predictive Calculator

Start date: January 2, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if the investigators can precisely predict how much pain medication the subjects will need after surgery using a special calculator that was developed for this purpose.