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Prolapse clinical trials

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NCT ID: NCT04480671 Active, not recruiting - Clinical trials for Pelvic Organ Prolapse

Impact of Level III Support Procedure on Enlarged Genital Hiatus After Minimally Invasive Sacrocolpopexy

MERIT
Start date: August 26, 2020
Phase: N/A
Study type: Interventional

This is a randomized controlled surgical trial evaluating the use of a concomitant posterior colporrhaphy and/or perineorrhaphy at the conclusion of minimally invasive sacrocolpopexy to narrow enlarged genital hiatuses in a population of women with pelvic organ prolapse. The study's primary outcome is the proportion of women at 6 months postoperatively who still have an enlarged genital hiatus. An exploratory sub-aim (as of October 2021) of the study is to evaluate the levator hiatal area as compared with the genital hiatus by using preoperative and postoperative transperineal ultrasounds. Subjects will be invited to participate, but is not required for study participation.

NCT ID: NCT04474275 Active, not recruiting - Clinical trials for Pelvic Organ Prolapse

The Effect of the Mode of Delivery to the Pelvic Floor Function

Start date: June 1, 2020
Phase:
Study type: Observational

The childbirth is one of the risk factors for pelvic organ prolapse. In order to prevent the pelvic organ prolapse, the physicians do not routinely advice any exercises after deliveries. The investigators wondered if the mode of deliveries such as ceserean section, vaginal route delivery with episiotomy or vaginal route delivery without episiotomy effect the pelvic floor function differently or not. In order to evaluate this, the investigators are planning to measure the muscle tonus in primiparous women.

NCT ID: NCT04410393 Active, not recruiting - Prolapse Clinical Trials

Sacrocolpopexy and Lateral Suspension Operations

Start date: June 1, 2020
Phase:
Study type: Observational

Different surgical methods can be used in the treatment of vaginal cuff prolapse in patients who had previously undergone hysterectomy for benign reasons. One of these is sacrocolpopexy and the other is lateral suspension. the investigators want to compare the results of patients undergoing these two operations. Thus, the difference between surgical methods will be investigated.

NCT ID: NCT04270188 Active, not recruiting - Clinical trials for Pelvic Organ Prolapse

Evolution of Symptoms After Anterior Sacrospinofixation by Autologous Tissues

SANTAU
Start date: July 21, 2020
Phase:
Study type: Observational

Prolapse is a pathology that can cause pelvic, urinary or sexual functional disorders and impaired quality of life. Although the use of vaginal mesh is a commonly practiced technique to correct prolapse, in recent years health officials have pointed to the lack of adequate safety and tolerability assessments of these implants. Currently, surgeons are therefore moving towards techniques without implants. The standard vaginal technique for the treatment of uterine prolapse is sacrospinofixation according to Richter. This technique can be performed without an implant, using autologous tissue. Functional discomfort of patients is the main problem linked to the presence of prolapse. However, no study has yet evaluated the feelings of patients following the use of this sacrospinofixation technique by autologous tissues by vaginal route, which led us to set up this study. The hypothesis is that the technique of anterior sacrospinofixation by autologous tissues improves the symptoms experienced by patients with an mid-level and / or anterior genital prolapse.

NCT ID: NCT04198714 Active, not recruiting - Surgery Clinical Trials

Pudendal Nerve Block in Vaginal Surgery

Start date: August 1, 2019
Phase: N/A
Study type: Interventional

The objective of this this randomized controlled study is to determine whether a pudendal nerve block at the time of vaginal surgery is associated with improved postoperative pain control and decrease opioid consumption compared to a sham pudendal nerve block in patients undergoing vaginal surgery.

NCT ID: NCT04179955 Active, not recruiting - Clinical trials for Pelvic Organ Prolapse

Intraoperative Costs and Patient Perceptions in Sacrocolpopexy for Prolapse

Start date: December 10, 2019
Phase:
Study type: Observational

Robotic sacrocolpopexy (a procedure for female pelvic organ prolapse) has been demonstrated to have equivalent surgical outcomes to open abdominal sacrocolpopexy and has been previously deemed more cost effective due to the longer hospital course following open procedures. The total cost of these procedures, including all costs of hospitalization as well as costs associated with the 30 days following surgery have previously been evaluated by the investigators. However, previous research is lacking in both the specific cost components that contribute to intraoperative cost of surgery as well as the patient perceived outcomes following these two procedures. This project aims to evaluate the marginal costs of surgery and to survey sacrocolpopexy patients to evaluate their satisfaction with outcomes and surgical scars.

NCT ID: NCT04072588 Active, not recruiting - Prolapse Clinical Trials

Sacrospinous Ligament Fixation and Lateral Suspension Operations

Start date: August 24, 2019
Phase:
Study type: Observational [Patient Registry]

Different surgical methods can be used in the treatment of vaginal cuff prolapse in patients who had previously undergone hysterectomy for benign reasons. One of these is transvaginal sacrospinous ligament fixation and the other is lateral suspension. the investigators want to compare the results of patients undergoing these two operations. Thus, the difference between surgical methods will be investigated.

NCT ID: NCT04013152 Active, not recruiting - Ulcerative Colitis Clinical Trials

Clinical Database of Colorectal Robotic Surgery

ROBOT CR
Start date: June 13, 2018
Phase:
Study type: Observational [Patient Registry]

Evaluation of robot Da Vinci Xi by determining its learning curve.The operating time will be defined by patient then the operating average will be calculated.

NCT ID: NCT03736811 Active, not recruiting - Clinical trials for Pelvic Organ Prolapse

Nonabsorbable Versus Absorbable Sutures for Anterior Colporrhaphy

Start date: November 8, 2018
Phase: N/A
Study type: Interventional

The objective of this is to compare surgical outcomes of anterior colporrhaphy using nonabsorbable sutures with anterior colporrhaphy using absorbable sutures.

NCT ID: NCT03714607 Active, not recruiting - Cystocele Clinical Trials

Laser Therapy in Managing Vaginal Prolapse

Start date: November 30, 2018
Phase: N/A
Study type: Interventional

Efficacy of laser therapy in postmenopausal women with symptomatic prolapse stage >1. Assessment tools will include prolapse stage quantification system (POP-Q) and validated condition related questionnaires.