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Clomiphene in Males With Prolactinomas and Persistent Hypogonadism

Hypogonadotropic Hypogonadism Clinical Trial

Official title:
Recovery of Gonadal Function by Clomiphene in Males With Prolactinomas and Persistent Hypogonadism

Clinical Trial Summary

Prolactinomas are usually associated with hypogonadotropic hypogonadism in both sexes. Clomiphene citrate is a well known selective estrogen receptor modulator that increases gonadotropin secretion via hypothalamic-pituitary action. We conducted a prospective, open label clinical trial of CC to evaluate its effects in reverting persistent HH in male patients with prolactinomas under dopaminergic agonist treatment.

Clinical Trial Description

n/a

Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00697814
Study type Interventional
Source Federal University of São Paulo
Contact
Status Completed
Phase Phase 2
Start date June 2004
Completion date June 2005
View Details
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