Procedural Sedation Clinical Trial
Official title:
Comparison Between Dexmedetomidine and Midazolam Nebulization as Procedural Sedation During Cesarean Delivery Under Spinal Anesthesia in Pre-eclamptic Parturients
Null hypothesis: There is no difference between the effects of nebulization of dexmedetomidine and midazolam as procedural sedation during cesarean delivery under spinal Anesthesia in pre-eclamptic parturients Alternative hypothesis: There is difference between the effects of nebulization of dexmedetomidine and midazolam as procedural sedation during cesarean delivery under spinal anesthesia in pre-eclamptic parturients
Site of study: This study will be carried out in operating theater of obstetrics at Zagazig University Hospitals. Withdrawal Criteria: The woman has the right to withdraw from the study at any time without any negative consequence on their medical or surgical treatment plan. Double -blind randomized clinical trial. All patients will be hospitalized and visited a day before the surgery, full history with physical examination and routine investigation will be done, the nature and complications of the study will be explained in detail to the patient and informed written consent will be obtained from every woman. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT03692390 -
Virtual Reality vs. Standard-of-Care for Comfort Before and After Sedation in the Emergency Department
|
N/A | |
| Completed |
NCT02145169 -
Inhaled Nitrous Oxide for the Prevention of Emergence Reaction During Ketamine Administration in Adults, a Pilot Study
|
N/A | |
| Recruiting |
NCT05595798 -
EEG Spectral Pattern of Deep Sedation-induced Airway Adverse Effects
|
||
| Completed |
NCT01260662 -
Randomized Clinical Trial of Propofol, 1:1 and 4:1 Combination of Propofol and Ketamine for Procedural Sedation
|
Phase 4 | |
| Completed |
NCT00784498 -
Procedural Sedation Using Propofol Versus Midazolam/Ketamine in the Adult Emergency Department
|
Phase 4 | |
| Completed |
NCT00327392 -
A Safety Study of AQUAVAN® (Fospropofol Disodium) Injection for Sedation During Minor Surgical Procedures.
|
Phase 2/Phase 3 | |
| Completed |
NCT03329014 -
A Trial of Intranasal Remimazolam Pharmacokinetics, Pharmacodynamics, Safety and Bioavailability
|
Phase 1 | |
| Recruiting |
NCT06414395 -
The Effects of Different Loading Doses of Dexmedetomidine on The Bispectral Index-Guided Propofol Sedation in Patients Undergoing Advanced Upper Gastrointestinal Endoscopic Procedures: A Randomized Control Study
|
Phase 4 | |
| Recruiting |
NCT03860831 -
Intranasal Ketamine and Midazolam Mixture for Procedural Sedation in Children With Mental Disabilities:
|
Phase 1 | |
| Completed |
NCT00869440 -
Dose-Finding Safety Study Evaluating Remimazolam (CNS 7056) in Patients Undergoing Diagnostic Upper GI Endoscopy
|
Phase 2 | |
| Not yet recruiting |
NCT05757622 -
Electroencephalogram Based Real-Time Sedation Level Prediction
|
||
| Completed |
NCT03799783 -
The Use of Dexmedetomidine for EEG Sedation in Children With Behavioural Disorders
|
Phase 2 | |
| Completed |
NCT02180737 -
Dexmedetomidine for Sedation During Radiological Interventional Procedures
|
Phase 4 | |
| Not yet recruiting |
NCT01227174 -
Safety and Efficacy of Propofol Only Sedation in Oral and Maxillofacial Surgery
|
Phase 4 | |
| Recruiting |
NCT03499886 -
Low-Dose Intravenous Ketamine Bolus Versus Conventional Technique
|
Phase 2/Phase 3 | |
| Completed |
NCT03747432 -
Comparison of Procedural Sedation With Propofol and Dexmedetomidine During Transcatheter Aortic Valve Implantation
|
Phase 4 | |
| Recruiting |
NCT06203522 -
Factors Associated With Successful Completion of MRI in Children Undergoing a Vigil Sedation With Dexmedetomidin
|
||
| Withdrawn |
NCT05783492 -
INK Feasibility Study
|
Phase 3 | |
| Recruiting |
NCT04686448 -
Ketofol Versus Fenofol as Procedural Sedation for Carpal Tunnel Release
|
Phase 1/Phase 2 | |
| Completed |
NCT02955732 -
Pharmacological Characteristics of Intranasally Given Dexmedetomidine in Paediatric Patients
|
Phase 4 |