Effect of Probiotics on Oral Homeostasis During Sugar Stress

Status Completed

Clinical Trial Summary

The present study is a double-blinded randomized clinical trial with a duration of 28 days.

Clinical Trial Description

The present study is a double-blinded randomized clinical trial with a duration of 28 days. 80 orally and systemically healthy participant will be allocated in the test (probiotic) and the control (placebo) group at baseline. The intervention is sugar stress, which will be applied at baseline and continue through day 14, followed by 14 days without sugar stress. Clinical measurements and sampling will be performed at baseline, day 14 and day 28 Primary endpoint: Changes in microbial composition. Secondary endpoints: Changes in clinical and immunological parameters ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05073393
Study type	Interventional
Source	University of Copenhagen
Contact
Status	Completed
Phase	N/A
Start date	November 3, 2021
Completion date	June 1, 2022

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04127929` - Investigation of Glass Carbomer Performance	N/A
Completed	`NCT04769882` - Er:YAG Laser Effects on Microbial Population in Conservative Dentistry	N/A
Completed	`NCT04971317` - The Influence of Simple, Low-Cost Chemistry Intervention Videos: A Randomized Trial of Children's Preferences for Sugar-Sweetened Beverages	N/A
Active, not recruiting	`NCT04475679` - Clinical Evaluation of Adhese Universal DC in the Indirect Restorative Therapy	N/A
Completed	`NCT05438381` - Comparison of Clinical and Radiographic Outcomes of SMART Technique vs ART in Primary Molars	N/A
Not yet recruiting	`NCT03037814` - Clinical Performance of Restorative Materials in Primary Teeth	N/A
Active, not recruiting	`NCT05202665` - Resin Infiltration and Fluoride Varnish Lesion Arresting Efficacy on Non-cavitated Proximal Lesion	N/A
Terminated	`NCT01147835` - Herbal Lollipops on Oral Bacterial Levels and DMFT/Dmft Scores of Children With Asthma Using Inhalers	N/A
Not yet recruiting	`NCT04033263` - Maintaining Oral Health With Bio-products	N/A
Enrolling by invitation	`NCT04438252` - Evaluation of Reliability of CarieScan PRO Compared With Digital Radiograph and ICDAS-II in Detection of Carious Lesions	N/A
Not yet recruiting	`NCT03609034` - Knowledge, Attitude and Practice of a Group of Egyptian Dental Interns Toward Caries Risk Assessment
Completed	`NCT02912000` - TEACH: Technology Evaluation to Address Child Health	N/A
Completed	`NCT02473107` - Impact of Detecting Initial and Active Caries Lesions in Primary Teeth	N/A
Active, not recruiting	`NCT02537184` - Impact of Two Recall Intervals on Dental Caries Incidence and Other Outcomes of Preschool Children	N/A
Completed	`NCT01950546` - Nanosilver Fluoride to Prevent Dental Biofilms Growth	Phase 1
Recruiting	`NCT02734420` - Effect of Photodynamic Therapy With Low-level Laser on Infected Dentin in Primary Teeth: A Controlled Clinical Trial	Phase 1
Completed	`NCT02020681` - Effect of Curodont Repair or Placebo on the Remineralisation in Patients With Class 5 Carious Lesions	N/A
Completed	`NCT02426619` - Arresting Active Dental Caries in Preschool Children by Topical Fluorides	Phase 2/Phase 3
Completed	`NCT02234609` - Effectiveness of Modified Class IV Atraumatic Restorative Treatment	N/A
Completed	`NCT02019563` - MTA/FS Pulpotomy for Vital Primary Incisors: A Randomized Controlled Trial	Phase 2