Investigation of TWK10 Administration on the Effects of Amino Acid

Status Completed

Clinical Trial Summary

The most common problem among sports people is that no matter how much protein food or products they eat, their sports performance cannot be improved, resulting in failure to achieve breakthroughs in sports performance. The cause of the trouble is digestion and absorption problems. The key is intestinal problems. If gastrointestinal function is maintained in a healthy state, then exercise performance must be maintained at a considerable level. Therefore, how to choose the source of protein in the diet is one of the most concerned issues of the sports crowd. Although past studies have confirmed that the essential amino acids in animal protein can be absorbed and utilized better than plant protein, plant protein can be broken down into easily digestible peptides and amino acids by pepsin. Promote the metabolite pool in the large intestine and the amino acid balance of the host in the small intestine. Recent studies have pointed out that the proteases and peptidases in lactic acid bacteria can provide free amino acids for the best growth of bacteria, and can increase the distribution of amino acids in the blood, the speed of muscle synthesis and the content of branched chain amino acids. However, the mechanism of action of Lactobacillus plantarum on protein digestion and amino acid absorption in the host is still unclear. Therefore, the purpose of this study is to explore the effect of supplementing sports lactic acid bacteria TWK10 in human experiments to effectively improve the amino acid bioabsorption rate of plant protein supplements. 40 subjects were randomly divided into 2 groups, each with 20 people (male and female): (1) pea protein without TWK10 (placebo), (2) TWK10 group (TWK10). The two groups of subjects were supplemented with test samples for 28 consecutive days and performed paired sports training 3 times a week. Before and after the intervention, the samples were subjected to exercise testing, blood and fecal sample collection, body composition analysis, and muscle mass analysis.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05412667
Study type	Interventional
Source	National Taiwan Sport University
Contact
Status	Completed
Phase	N/A
Start date	November 1, 2021
Completion date	May 1, 2022

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05156424` - A Comparison of Aerobic and Resistance Exercise to Counteract Treatment Side Effects in Men With Prostate Cancer	Phase 1/Phase 2
Completed	`NCT05108181` - Muscle Typology and Strength Training Adaptations	N/A
Recruiting	`NCT05052918` - The Effect of Exercise and Metformin on Carotid Intima-media Thickness in Patients With Prediabetes	N/A
Completed	`NCT04508270` - Significance of Early Mobilization After VATS-L
Recruiting	`NCT04994340` - Physical Activity Observatory of Castilla-La Mancha
Completed	`NCT04815980` - Impact of Pilates on Running Mechanics	N/A
Completed	`NCT05189795` - The Construction of Physical ACtivity Enhancement Scheme (PACES) in Hemodialysis Patients
Completed	`NCT03683758` - Effects of the FIFA11+ Warm-up Program on Speed, Agility, and Vertical Jump Performance in Adult Female Amateur Soccer Players	N/A
Completed	`NCT05538520` - Effects of Pilates Stretching on Flexibility, Strength, Power and Muscular Endurance	N/A
Completed	`NCT06315036` - Effects of Developmental Gymnastics on Preschoolers' Motor Skills	N/A
Completed	`NCT03171064` - Exercise as a Supportive Measure for Patients Undergoing Checkpoint-inhibitor Treatment	Phase 2
Recruiting	`NCT05496751` - Response Variability to Exercise	N/A
Not yet recruiting	`NCT05029804` - Effect of Walking Exercise Training on Adherence to Disease Management and Metabolic Control in Diabetes	N/A
Completed	`NCT04207359` - Effects of Creatine Supplementation in Breast Cancer Survivors	N/A
Completed	`NCT03832205` - Validation of Respiratory Rate and Heart Rate Measurements by Capaciflectors Placed in Four Locations on the Chest
Completed	`NCT04099654` - The Effect of Core Stabilization Exercise Program in Obese Subjects Awaiting Bariatric Surgery	N/A
Completed	`NCT03297567` - Physical Therapy Guidelines For Hospitalized Elderly	N/A
Completed	`NCT03477188` - The Effects of Somatosensory and Vestibular Rehabilitation Additional Conventional Therapy on Balance in Patients With Acute Stroke.	N/A
Recruiting	`NCT05956327` - Insight Into Hippocampal Neuroplasticity in Schizophrenia by Investigating Molecular Pathways During Physical Training	N/A
Recruiting	`NCT06018311` - Exercising Together for Hispanic Prostate Cancer Survivor-Caregiver Dyads	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Investigation of TWK10 Administration on the Effects of Amino Acid Absorption

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms