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Primary Sjögren's Syndrome clinical trials

View clinical trials related to Primary Sjögren's Syndrome.

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NCT ID: NCT05673993 Recruiting - Clinical trials for Primary Sjogren's Syndrome

A Study to Evaluate the Efficacy and Safety of Telitacicept in Subjects With Active Primary Sjogren's Syndrome

Start date: April 7, 2023
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of subcutaneous Telitacicept versus placebo in subjects with active primary Sjogren's Syndrome.

NCT ID: NCT05087589 Recruiting - Clinical trials for Primary Sjögren's Syndrome

Efficacy, Safety and Immunological Evaluation of Tofacitinib in the Treatment of Primary Sjogren's Syndrome

Start date: November 20, 2021
Phase: Phase 2
Study type: Interventional

This study aims to explore the clinical and immunological efficacy of tofacitinib on primary Sjögren's Syndrome

NCT ID: NCT04981145 Recruiting - Clinical trials for Primary Sjögren's Syndrome

The Efficacy and Safety of Iguratimod (IGU) in the Treatment of Primary Sjögren's Syndrome

Start date: January 14, 2022
Phase: Phase 4
Study type: Interventional

A multi-center, prospective, open-label, randomized controlled study of efficacy and safety of Iguratimod in patients with Primary Sjögren's syndrome

NCT ID: NCT04858464 Recruiting - Clinical trials for Primary Sjögren's Syndrome

Reliability, Validity of the Turkish Version of the Primary Sjögren Syndrome Quality of Life (PSS-QoL) Questionnaire

Start date: May 2, 2021
Phase:
Study type: Observational

The purpose of this study was to investigate adaptation, validity, and reliability of the Turkish version of the Primary Sjögren's Syndrome Quality of Life (PSS-QoL) Questionnaire

NCT ID: NCT04544722 Recruiting - Clinical trials for Interstitial Lung Disease

Clinical Study of Jianfei Kangfu Cao in the Treatment of pSS-ILD

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

This study will evaluate the safety and efficacy of Jianfei Kangfu Cao in the treatment of primary Sjogren's syndrome associated interstitial lung disease.

NCT ID: NCT04212572 Recruiting - Clinical trials for Primary sjögren's Syndrome

Ultrasound Abnormalities of the Salivary Glands in Primary Sjögren's Syndrome According to the Duration of the Disease

MASAÏ
Start date: November 20, 2019
Phase:
Study type: Observational

Salivary gland ultrasonography is identified as a valuable diagnostic tool and potential criteria item for disease classification of sjögren's syndrome and evaluate evolution of parenchyma. The investigators have to include 242 patients. The objective is to evaluate the modification of ultrasonographic abnormalities according to disease in primary Sjögren syndrome.

NCT ID: NCT03040583 Recruiting - Clinical trials for Primary Sjögren's Syndrome

The ASSESS National Multi-center Prospective Cohort

ASSESS
Start date: September 2016
Phase:
Study type: Observational [Patient Registry]

The ASSESS national multi-center prospective cohort (Assessment of Systemic complications (Signs) and Evolution in Sjögren's Syndrome "SS") was set up in 2006 thanks to a grant of the French Ministry of Health. Fifteen centers for autoimmune diseases consecutively included consecutive patients with Primary Sjögren's Syndrome "pSS" fulfilling American-European Consensus Criteria (AECG) between 2006 and 2009. The study was approved by the Ethics Committee of Bichat Hospital in 2006. All patients gave their informed written consent. This study was followed for 5 years with the grant of the French Ministry of Health and this study will be extended for 20 years by French Society of Rheumatology (SFR). On an annual basis for a duration of 20 years, a thorough standardized paper case report form (CRF) was filled prospectively by clinicians.

NCT ID: NCT03003572 Recruiting - Clinical trials for Primary Sjögren's Syndrome

Autoreactive Anti-Ro/SSA IgE To Determine Primary SjögRen's Syndrome's Disease Activity

I GET DRY
Start date: March 27, 2018
Phase:
Study type: Observational

Primary Sjögren's syndrome (pSS) can affect various organs, sometimes leads to life-threatening conditions and is always responsible for a decreased quality of life. Its evolution is chronic, with flares and relapses, and the need for reliable biomarkers to be carried out routinely is major in patients' follow-up. Because of the existence of autoreactive immunoglobulins E (IgE) in autoimmune diseases, the recently described role for anti-Ro/SSA antibodies in inducing interferon alpha (IFNα) signaling and the specific pharmacologic properties of IgE, anti-Ro/SSA IgE should be an interesting biomarker to determine pSS's activity. The aim of the study is to evaluate whether the proportion of anti-Ro/SSA IgE positive patients is higher in patients with active disease (i.e. Eular Sjögren Syndrome Disease Activity Index≥ 5). All consecutive patients with pSS (new or already known diagnosis) will be included, Anti-Ro/SSA IgE titers will be determined, the disease's features will be collected (including Eular Sjögren Syndrome Disease Activity Index/Eular Sjogren's Syndrome Patient Reported Index).

NCT ID: NCT01501019 Recruiting - Myositis Clinical Trials

Exercise in Sjogren, Myositis and Takayasu's Arteritis

Start date: October 2011
Phase: N/A
Study type: Interventional

Exercise may improve physical capacity and health parameters in Primary Syndrome´s Sjogren, Myositis and Takayasu's Arteritis. Therefore, this study aims to investigate the role of an exercise training program in patients with Primary Syndrome´s Sjogren, Myositis and Takayasu's Arteritis.