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Vidofludimus Calcium for Primary Sclerosing Cholangitis — PSC  

Primary Sclerosing Cholangitis Clinical Trial

Official title:
Investigation of the Activity of Vidofludimus Calcium, a Novel, Orally Available, Small Molecule Inhibitor of Dihydroorotate Dehydrogenase, as a Treatment for Primary Sclerosing Cholangitis (PSC)

Clinical Trial Summary

To examine the safety, tolerability, and efficacy of daily dosing with vidofludimus calcium over a 6-month period.

Clinical Trial Description

Investigators will assess the following: 1. Changes on serum alkaline phosphatase levels at 3 & 6 months. 2. Changes in other liver biochemistries at 3 & 6 months. 3. Changes in IL-17 &IFNγ levels at 6 weeks and 6 months. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03722576
Study type Interventional
Source Mayo Clinic
Contact
Status Completed
Phase Phase 2
Start date June 17, 2019
Completion date June 30, 2020
View Details
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