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Clinical Trial Summary

This study will enroll male and female subjects who are 18 years of age or older with Primary Myelofibrosis, post-polycythemia Vera Myelofibrosis, or post-essential Thrombocythemia Myelofibrosis with severe thrombocytopenia (platelet count <50,000/µL) including subjects with intermediate-1, intermediate-2, or high-risk MF according to the Dynamic International Prognostic Scoring System (DIPSS).


Clinical Trial Description

NS-018 will be self-administered orally at a dose of 300 mg BID. The BAT will be administered according to manufacturer's instructions and Investigator discretion. Subjects will complete study visits at Screening, Day 1 and Day 15 of Cycle 1, 2, 3, 4, 5, 6 and Day 1 of every cycle thereafter. At these visits, blood/urine sampling, spleen measurements, bone marrow assessments, patient-reported outcome (PRO) assessments, and safety assessments may be performed. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04854096
Study type Interventional
Source NS Pharma, Inc.
Contact NS Pharma, Inc.
Phone 201-986-3860
Email [email protected]
Status Not yet recruiting
Phase Phase 2
Start date July 1, 2021
Completion date April 24, 2024

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