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REmission in Membranous Nephropathy International Trial (REMIT) — REMIT  

Primary Membranous Nephropathy Clinical Trial

Official title:
International, Multi-centre Randomised Clinical Trial of Obinutuzumab Versus Corticosteroid and Cyclophosphamide in Primary Membranous Nephropathy (REMIT Trial).

Clinical Trial Summary

REMIT is an investigator-initiated, international, multi-centre, prospective, randomised, open-label, parallel-group trial. A total of 224 adult participants with Primary Membranous Nephropathy (PMN) will be recruited from renal units from Australia, New Zealand Canada, Asia, Europe, United Kingdom, and other countries. Participants will be randomised to receive either corticosteroid and cyclophosphamide or obinutuzumab. The primary outcome is a ranked, composite measure based on (a) efficacy, defined as either complete or partial remission of PMN, (b) number of adverse events, and (c) quality of life.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06120673
Study type Interventional
Source The University of Queensland
Contact Peta-Anne Paul-Brent
Phone +61411 397 776
Email remit@uq.edu.au
Status Not yet recruiting
Phase Phase 3
Start date July 31, 2024
Completion date January 31, 2028
View Details
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