Primary Liver Cancer Cohort of South China

Primary Liver Cancer Clinical Trial

Official title:

Factors Influencing the Occurrence and Long-term Survival of Patients With Primary Liver Cancer: A Cohort Study in South China

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03297255
• Other study ID #: SYS-2013
• Status: Recruiting
• Phase: N/A
• First received: September 25, 2017
• Last updated: September 27, 2017
• Start date: January 1, 2013
• Est. completion date: December 2025

Study information

• Verified date: September 2017
• Source: Sun Yat-sen University
• Contact: Zhu Huilian, Professor
• Phone: +86 20 87331811
• Email: zhuhl[@]mail.sysu.edu.cn
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This longitudinal observational cohort study was designed to investigate factors that influencing the occurrence and long-term survival of patients with primary liver cancer. Basic informations and detailed diagnosis informations (AJCC/TNM stage, MELD score, Child-Pugh score, and BCLC stage) were collected by professional doctors. Clinical outcomes (death, recurrence, and metastasis) will be followed up every two years after therapy.

Description:

Primary liver cancer (PLC) is highly malignant with high mortality which is particularly popular in China. Many factors are believed to associate with the occurrence and prognosis of liver cancer. This longitudinal observational cohort study was designed to investigate factors that influencing the occurrence and long-term survival of patients with primary liver cancer.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 4000
• Est. completion date: December 2025
• Est. primary completion date: December 2025
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• age 18-80 years

• consistent with primary liver cancer diagnostic criteria

• first diagnosis (from diagnosis to admission interval of less than a month)

• did not do any treatment of liver cancer

Exclusion Criteria:

• refused to participate in this study

• suffering from more than two kinds of primary tumors

Related Conditions & MeSH terms

• Liver Neoplasms
• Primary Liver Cancer

Locations

Country	Name	City	State
China	Sun Yat-sen University Cancer Center	Guangzhou	Guangdong

Sponsors (1)

Lead Sponsor	Collaborator
Huilian Zhu

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Time of Death	The exact death time of each participants will be checked in the government medical records system	Up to 10 years
Secondary	Time of recurrence	Time of recurrence will be obtained by telephone interview or medical treatment records	From date of diagnosis until the date of cancer recurrence or date of death from any cause, whichever came first, assessed up to 10 years
Secondary	Time of metastasis	Time of metastasis will be obtained by telephone interview or medical treatment records	From date of diagnosis until the date of cancer metastasis or date of death from any cause, whichever came first, assessed up to 10 years